Spinal Cord Stimulation Tested in Adults With Back Pain and High Blood Pressure
Tests whether spinal cord stimulation lowers blood pressure in adults with back pain.
Plain-language title generated from the registry record
Registry title: Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
Key facts
- Where
- Birmingham, United StatesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 89 years old?
Source: NCT05556902, who can take part
Where in United States
- University of Alabama at BirminghamBirmingham, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Alabama at Birmingham
- Trial code
- NCT05556902
- Record updated
- 11 August 2026
- Original description
The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions in pain following SCS, and finally 3) whether different SCS waveforms elicits stimulus-evoked compound action potentials (ECAPs) in spinal cord and at the cortex (electroencephalography, and magnetoenchphalography).Read full original descriptionShow less
Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions in pain following SCS, and finally 3) whether different SCS waveforms elicits stimulus-evoked compound action potentials (ECAPs) in spinal cord and at the cortex (electroencephalography, and magnetoenchphalography).
Inclusion: Male or Female, age 18-89; Chronic pain for more than 3 months; Willing to visit a research lab; Willing to undergo a blood draw; Able to provide written informed consent.
Exclusion: History of neurological disease (e.g., dementias, Parkinson's); History of stroke; Current diagnosis of cancer; Subject is unwilling or unable to comply with the protocol.