CompletedNo phase
Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement
Key facts
- Who runs it
- Baylor Research Institute
- Where
- Dallas, Fort Worth, Plano, and Temple, United StatesSee the 4 sites
- Trial code
- Status
- Completed
- People taking part
- 81 people enrolled
- Started
- 17 Jan 2022
- Ended
- 27 Feb 2024
- Type of study
- Observational
- Treatments tested
- 5 minute Montreal Cognitive Assessment (mini MoCA)
- Record updated
- 27 January 2026
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 5 criteriaShow less
Who can take part
- Age 18 years or older
- Undergoing a TAVR procedure
- Possible MCI as determined by procedures already used in the TAVR clinics, including 1 of the 4:; MMSE < 27; History of MCI, dementia, or stroke (CVA or TIA); History of prescription treatment for MCI; Discretion of the investigator, physician, or clinic staff
- Scores 25 or less on the mini MoCA exam
Who cannot take part
- In another research study that doesn't allow dual enrolment, or dual enrolment has not been granted
Where in United States
- Baylor Heart and Vascular HospitalDallas, United StatesNo longer taking part
- Baylor Scott & White All Saints at Fort WorthFort Worth, United StatesNo longer taking part
- Baylor Scott and White - The Heart Hospital Baylor PlanoPlano, United StatesNo longer taking part
- Baylor Scott & White Medical Center - TempleTemple, United StatesNo longer taking part
About the trial
What the trial wants to find out
This trail is for patients with mild cognitive impairment (MCI) who are receiving a transcatheter aortic valve replacement (TAVR). We will assess changes in neurocognition following TAVR with the 5 minute Montreal Cognitive Assessment (mini MoCA) when comparing pre procedure with post procedure assessments.
The group in the trial
- Patients with Mild Cognitive Impairment Undergoing TAVR
Patients will be treated with standard of care. In addition, patients will complete the mini MoCA at 3 time points
Treatment: 5 minute Montreal Cognitive Assessment (mini MoCA)
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement: Periprocedural Changes and Predictors of Improvement
- Record updated
- 27 January 2026