Breathing and Blood Pressure Study in Adults With and Without Obesity
Studies how obesity affects heart and blood pressure responses during breathing exercises.
Key facts
- Who runs it
- Florida State University
- Where
- Tallahassee, United StatesSee the site
- Trial code
- Registry title
- Breathing & Blood Pressure
- Status
- Recruiting
- People taking part
- 80 people, planned
- Started
- 25 Oct 2023
- Expected to end
- 30 Jun 2027
- Type of study
- Observational, 2 groups
- Record updated
- 7 October 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 45 with a body mass index of 40 kg/m^2 or less. It studies how obesity affects blood pressure and heart responses during breathing exercises.
- Age
- 18 Years to 45 Years
- Sex
- All sexes
- Earlier treatment
- People must not have had bariatric surgery. Body weight must have been stable over the past six months.
- Biomarker or test result
- Body mass index of 40 kg/m^2 or less.
Main reasons for not taking part
- Heart, nerve, kidney, liver or metabolic illness, such as diabetes
- Stage 2 hypertension that is or was uncontrolled
- Diagnosed obstructive sleep apnea or airway disease
- Use of tobacco or nicotine products in the past 6 months
- Pregnant, breastfeeding or post-menopausal women
The registry criteria, word for word
Show all 18 criteriaShow less
Who can take part
- Body mass index values of ≤40 kg/m\^2
Who cannot take part
- Previous bariatric surgery
- Patients who have undergone recent abdominal surgery and those with abdominal hernia
- Overt cardiovascular, neurological, renal, liver, and/or metabolic illness (e.g., diabetes mellitus)
- Current, or history of uncontrolled, Stage 2 hypertension (blood pressure >140 / 90 mmHg; anti-hypertensive medications are permitted)
- Diagnosis or signs (e.g., values below the lower limit of normal) of overt airway disease(s)
- If a patient is suffering from a ruptured eardrum or any other condition of the ear
- Patients with worsening heart failure signs and symptoms after a respiratory/inspiratory muscle training (IMT) session
- If you are suffering from a cold, sinusitis, or respiratory tract infection, we advise that you do not use your POWERbreathe IMT device
- Not weight stable (<5% change in body mass over the past six months)
- Diagnosed obstructive sleep apnea
- Current or recent (regular use within the past 6 months) use of tobacco or nicotine products (e.g., cigarettes, vaping)
- Per the POWERbreathe® company:
- Asthma patients who have a very low symptom perception and suffer from frequent, severe exacerbations or with an abnormally low perception of dyspnoea
- Patients with marked elevated left ventricular end-diastolic volume and pressure
- Individuals who are not yet adults (infants, children, teenagers)
- Pregnant (self-reported and urine pregnancy test conducted), lactating (self-reported), or post-menopausal (self-reported) females
- Prisoners
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Where in United States
- Florida State UniversityTallahassee, United StatesContact: Joseph Watso, PhDTaking people
About the trial
What the trial wants to find out
The purpose of this study is to determine the effect of obesity on cardiovascular responses during various breathing maneuvers.
The 2 groups in the trial
- Adults without obesity
body mass index below 30 kg/m\^2
- Adults with obesity
body mass index above 30 kg/m\^2
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Breathing & Blood Pressure
- Plain-language title
- Breathing and Blood Pressure Study in Adults With and Without ObesityGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT05632406, who can take part
- Record updated
- 7 October 2026