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Breathing and Blood Pressure Study in Adults With and Without Obesity

Studies how obesity affects heart and blood pressure responses during breathing exercises.

Plain-language title generated from the registry record
Registry title: Breathing & Blood Pressure

Key facts

Where
Tallahassee, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 45 years old?

Source: NCT05632406, who can take part

Where in United States

  • Florida State UniversityTallahassee, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Florida State University
Trial code
NCT05632406
Record updated
7 October 2026
Original description
The purpose of this study is to determine the effect of obesity on cardiovascular responses during various breathing maneuvers.Read full original descriptionShow less

Breathing & Blood Pressure

The purpose of this study is to determine the effect of obesity on cardiovascular responses during various breathing maneuvers.

Inclusion: Body mass index values of ≤40 kg/m\^2.

Exclusion: Previous bariatric surgery; Patients who have undergone recent abdominal surgery and those with abdominal hernia; Overt cardiovascular, neurological, renal, liver, and/or metabolic illness (e.g., diabetes mellitus); Current, or history of uncontrolled, Stage 2 hypertension (blood pressure >140 / 90 mmHg; anti-hypertensive medications are permitted); Diagnosis or signs (e.g., values below the lower limit of normal) of overt airway disease(s); If a patient is suffering from a ruptured eardrum or any other condition of the ear; Patients with worsening heart failure signs and symptoms after a respiratory/inspiratory muscle training (IMT) session; If you are suffering from a cold, sinusitis, or respiratory tract infection, we advise that you do not use your POWERbreathe IMT device; Not weight stable (<5% change in body mass over the past six months); Diagnosed obstructive sleep apnea; Current or recent (regular use within the past 6 months) use of tobacco or nicotine products (e.g., cigarettes, vaping); Per the POWERbreathe® company:; Asthma patients who have a very low symptom perception and suffer from frequent, severe exacerbations or with an abnormally low perception of dyspnoea; Patients with marked elevated left ventricular end-diastolic volume and pressure; Individuals who are not yet adults (infants, children, teenagers); Pregnant (self-reported and urine pregnancy test conducted), lactating (self-reported), or post-menopausal (self-reported) females; Prisoners.

ClinicalTrials.gov NCT05632406