Tests a pre-transplant exercise and diet program in older adults with myeloma
Tests exercise and diet before stem cell transplant in adults 60 or older with myeloma.
Plain-language title generated from the registry record
Registry title: Prehabilitation Feasibility Among Older Adults Undergoing Transplantation
Key facts
- Where
- Birmingham, United StatesSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 60 or older with multiple myeloma who are scheduled for an autologous stem cell transplant at UAB. It tests a program to prepare the body before the transplant.
- Age
- 60 years or older
- Sex
- All sexes can join
- Disease stage
- Multiple myeloma, scheduled for an autologous stem cell transplant (ASCT) at UAB within 10 weeks of joining
Main reasons for not taking part
- High risk of an impending pathologic fracture (bone break), judged with the Mirels score
Read by machine on 9 November 2026.
Where in United States
- Kirklin Clinic of UAB HospitalBirmingham, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Noha Mohamed Sharafeldin
- Trial code
- NCT05642884
- Record updated
- 24 December 2025
- Original description
This is a pilot feasibility trial among older adults (≥60y) scheduled to undergo Autologous Stem Cell transplantation at UAB. Participants will be randomized into either a prehabilitation program or an attention control group before their transplant. The primary outcomes will be feasibility and secondary outcomes include changes in physical function at the time of transplant and at 12 weeks follow up.Read full original descriptionShow less
Feasibility of a Prehabilitation Intervention Among Older Adults With Myeloma Receiving Autologous Stem Cell Transplant
This is a pilot feasibility trial among older adults (≥60y) scheduled to undergo Autologous Stem Cell transplantation at UAB. Participants will be randomized into either a prehabilitation program or an attention control group before their transplant. The primary outcomes will be feasibility and secondary outcomes include changes in physical function at the time of transplant and at 12 weeks follow up.
Inclusion: Diagnosis of Multiple Myeloma; Scheduled for ASCT at UAB within 10 weeks of study enrollment; age at ASCT ≥60y.
Exclusion: at high risk for impending pathologic fracture using Mirels score.