Following Biologic Treatment Outcomes in Stricturing Crohn's Disease
Studies how biologic medicines work in people with narrowing Crohn's disease.
Key facts
- Who runs it
- Jinling Hospital, China
- Where
- Nanjing, ChinaSee the site
- Trial code
- Registry title
- Biologics for Stricturing Crohn's Diseases
- Status
- Recruiting
- People taking part
- 200 people, planned
- Started
- 1 Jan 2021
- Expected to end
- Jan 2029
- Type of study
- Observational
- Treatments tested
- treat these patients with biologics
- Record updated
- 11 May 2023
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for people aged 16 to 65 with Crohn's disease that has caused narrowing of the bowel (strictures) and who do not need surgery. They will be treated with biologic medicines and followed.
- Age
- 16 to 65 years
- Sex
- All sexes can join.
- Disease stage
- Crohn's disease with bowel narrowing (stricturing). No need for surgery. Penetrating disease is allowed only if it causes no symptoms.
Main reasons for not taking part
- Needs surgery
- Penetrating disease that causes symptoms
- Cannot take biologic medicines (contraindication)
- Planning to join another trial
The registry criteria, word for word
Show all 8 criteriaShow less
Who can take part
- patients with stricturing Crohn's diseases
- no surgical indication
- patients with asymptomatic penetrating diseases
- written consent acquired
Who cannot take part
- patients with surgical indication
- patients with symptomatic penetrating diseases
- contraindication of biologics
- anticipating other trial
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 16 and 65 years old?
Where in China
- Department of General Surgery, Jinling hosptal,Medical School of Nanjing UniversityNanjing, ChinaContact: Weiming Zhu, PhDTaking people
About the trial
What the trial wants to find out
Recent researches have reported that biologics might be also effective for stricturing CD. However, the data were largely retrospective. Prospective studied are needed for evaluate the efficacy of biologics for stricturing Crohn's diseases.
The group in the trial
- Patients with stricturing Crohn's diseases
Treatment: treat these patients with biologics
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- The Clinical Outcomes of Patients With Stricturing Crohn's Diseases Received Biologics: a Prospective, Observative Study
- Plain-language title
- Following Biologic Treatment Outcomes in Stricturing Crohn's DiseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT05645055, who can take part
- Record updated
- 11 May 2023