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Collects information on redifferentiating medicines for thyroid cancer not responding to radioactive iodine

Collects information on adults with radioactive iodine-refractory thyroid cancer treated with redifferentiating medicines.

Plain-language title generated from the registry record
Registry title: A Study to Collect Information About the Use of Redifferentiating Medications as a Standard Treatment for Thyroid Cancer

Key facts

Where
New York, United StatesSee the site

Where in United States

  • Memorial Sloan-Kettering Cancer CenterNew York, United StatesTaking people

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  4. What happens if I want to stop?
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Trial details

Who runs it
Memorial Sloan Kettering Cancer Center
Trial code
NCT05733013
Record updated
27 April 2026
Original description
The purpose of this study to learn more about the use of redifferentiating medications as a standard treatment for radioactive iodine/RAI-refractory thyroid cancer. This study is a registry study.Read full original descriptionShow less

Outcomes of Patients With Thyroid Carcinoma Treated With Redifferentiating Agents as Part of Routine Clinical Care: A Prospective Data Collection Study

The purpose of this study to learn more about the use of redifferentiating medications as a standard treatment for radioactive iodine/RAI-refractory thyroid cancer. This study is a registry study.

Inclusion: Patients ≥ 18 years old at time of consent; Patients diagnosed with RAI refractory thyroid cancer or unlikely to respond to RAI; Patients who will receive redifferentiation agents prior to planned diagnostic and/or therapeutic use of radioactive iodine as part of routine clinical care; Patients who have never received redifferentiation agents outside of a clinical trial or have received redifferentiation agents in the context of a clinical trial will be enrolled after the clinical team has decided to proceed with a redifferentiation agent as part of routine clinical care prior to diagnostic and/or therapeutic radioactive iodine administration; Patients previously treated with redifferentiation agents as part of clinical care prior to diagnostic and/or therapeutic radioactive iodine administration who are willing to provide retrospectively collected data surrounding the time of the previous treatment and will provide prospective data from the time of consent.

Exclusion: RAI refractory thyroid cancer patients that will receive redifferentiation agents prior to diagnostic and/or therapeutic use of radioactive iodine as part of a prospective clinical trial.

ClinicalTrials.gov NCT05733013