Testing Light Therapy for Multiple Myeloma Patients Receiving Stem Cell Transplants
Tests two light treatments aimed at body clock balance in adults with multiple myeloma.
Plain-language title generated from the registry record
Registry title: The Ambient Light Multiple Myeloma Study
Key facts
- Where
- New York, United StatesSee the 2 sites
Where in United States
- Icahn Schoool of Medicine at Mount SinaiNew York, United StatesTaking people
- Memorial Sloan-Kettering Cancer CenterNew York, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Icahn School of Medicine at Mount Sinai
- Trial code
- NCT05737732
- Record updated
- 12 June 2026
- Original description
The aim of this multi-site randomized control trial will be is to assess the impact Systematic lighting on circadian rhythm entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation. To achieve this aim, 200 multiple myeloma patients will receive one of two different light-treatments that are designed to promote circadian rhythm alignment. While receiving these light treatments, participants' sleep efficiency, urine melatonin levels, blood inflammatory cytokine levels and symptoms will be assessed over a 2-month period.Read full original descriptionShow less
Systematic Light Exposure Effects on Circadian Rhythms Entrainment, Inflammation, Neutropenic Fever and Symptom Burden Among Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation
The aim of this multi-site randomized control trial will be is to assess the impact Systematic lighting on circadian rhythm entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation. To achieve this aim, 200 multiple myeloma patients will receive one of two different light-treatments that are designed to promote circadian rhythm alignment. While receiving these light treatments, participants' sleep efficiency, urine melatonin levels, blood inflammatory cytokine levels and symptoms will be assessed over a 2-month period.
Inclusion: Multiple Myeloma diagnosis; Scheduled to undergo their first Autologous Stem Cell Transplant procedure; 21years or older; Able to provide informed consent; English-language proficient.
Exclusion: Previous Autologous Stem Cell Transplant procedure; Previous use of light therapy; Eye diseases which limit the ability of light to be processed; Secondary cancer diagnosis within the last 5 years; Severe sleep disorders; History of bipolar disorder or manic episodes; Severe psychological impairment; Active infection including COVID-19 infection; Pregnancy.