Studies pregnancy outcomes in women with obesity, diabetes or past bariatric surgery
Observes pregnancies in women with obesity, diabetes or prior weight-loss surgery.
Plain-language title generated from the registry record
Registry title: Effect of Obesity, Diabetes and Bariatric Surgery on Pregnancy Outcomes
Key facts
- Where
- London, United KingdomSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Source: NCT05753124, who can take part
Where in United Kingdom
- Chelsea & Westminster Hospital Nhs FtLondon, United KingdomTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Chelsea and Westminster NHS Foundation Trust
- Trial code
- NCT05753124
- Record updated
- 3 March 2023
- Original description
The obesity epidemic is growing worldwide and in the UK this is perpetuated with a third of women classified as overweight/obese in 2020. Many of these woman are of childbearing age and go on to have high risk pregnancies which are often complicated by gestational or pre-existing (type 2 diabetes mellitus (GDM, T2DM). Bariatric surgery is the most successful treatment of sustainable weight loss and is associated with a reduction in rates of GDM, pre-eclampsia, delivery of large babies but increased risk of delivery of small babies and preterm delivery.Read full original descriptionShow less
Investigation and Study of Pregnancy in Overweight or Diabetic Women and the Effect of Bariatric Surgery on Pregnancy Outcomes
The obesity epidemic is growing worldwide and in the UK this is perpetuated with a third of women classified as overweight/obese in 2020. Many of these woman are of childbearing age and go on to have high risk pregnancies which are often complicated by gestational or pre-existing (type 2 diabetes mellitus (GDM, T2DM). Bariatric surgery is the most successful treatment of sustainable weight loss and is associated with a reduction in rates of GDM, pre-eclampsia, delivery of large babies but increased risk of delivery of small babies and preterm delivery.
The aims of the study are to investigate the maternal and fetal/neonatal, biophysical and biochemical, intra-uterine environment and postnatal profile of pregnancies:
1. affected by maternal obesity and/or GDM/T2DM compared to pregnancies with normal maternal body mass index (BMI). 2. with previous maternal bariatric surgery compared to pregnancies without previous bariatric surgery but matched for maternal pre-surgery and early pregnancy BMI.
Inclusion: Pregnant women with normal size (BMI <30); Pregnant women with obesity (BMI ≥30); Pregnant women with glucose disorders; Pregnant women with previous bariatric surgery.
Exclusion: Pregnant women less than 18 years of age; Pregnant women with twins/triplets.