Studies how food, gut bacteria and genes affect blood sugar in type 1 diabetes
Observes how diet, gut microbes and genes shape blood sugar after meals in adults.
Key facts
- Who runs it
- Federico II University
- Where
- Naples, ItalySee the site
- Trial code
- Registry title
- Evaluation of Main Determinants of Postprandial Glucose Response in Type 1 Diabetes
- Status
- Recruiting
- People taking part
- 200 people, planned
- Started
- 18 May 2021
- Expected to end
- Jan 2028
- Type of study
- Observational
- Record updated
- 19 September 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with type 1 diabetes. It studies what affects blood sugar after meals, using a glucose sensor.
- Age
- 18 Years to 70 Years
- Sex
- All sexes can join.
- Disease stage
- Type 1 Diabetes
- Earlier treatment
- People who used antibiotics in the past 3 months cannot join.
Main reasons for not taking part
- Pregnancy and/or breastfeeding
- Other chronic or acute diseases
- Use of antibiotics in the past 3 months
The registry criteria, word for word
Show all 4 criteriaShow less
Who can take part
- Type 1 Diabetes
Who cannot take part
- Other chronic or acute diseases
- Pregnancy and/or breastfeeding
- Use of antibiotics in the past 3 months
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Where in Italy
- Federico II University HospitalNaples, ItalyContact: Giovanni Annuzzi, M.D.Taking people
About the trial
What the trial wants to find out
The goal of this observational study is to explore inter- and intra-individual determinants of postprandial glucose response in patients with type 1 diabetes using continous glucose monitoring (CGM).
Read full original descriptionShow less
Blood samples and anthropometrics will be collected during hospital visit. Participants will be asked to:
* record a seven-day food diary * complete EPIC food frequency questionnaire * complete questionnaires on sleep hygiene * collect a stool sample
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Evaluation of the INteraction Between Diet, microbiomE and Epigenetic Towards Personalized Interventions in Type 1 Diabetes (IN-DEEP Study)
- Plain-language title
- Studies how food, gut bacteria and genes affect blood sugar in type 1 diabetesGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT05936242, who can take part
- Publications
- Ultra-processed food intake and its associations with atherogenic dyslipidemia, glycemic control, and gut microbiome features in adults with type 1 diabetes from Southern Italy.Diabetes research and clinical practice, 2026
- Gut microbiome profiles and associated functional pathways are linked to Mediterranean diet adherence and blood glucose control in adults with type 1 diabetes mellitus.Nutrition, metabolism, and cardiovascular diseases : NMCD, 2026
- Record updated
- 19 September 2025