Type 1 diabetes trials in Italy

In Italy 30 Also abroad 537

30 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Real-World Study of Patients With Type 1 Diabetes Treated With Teplizumab as Part of Managed Access Programs (MAPs)
Where
Ancona, Palermo, Verona
People
60 worldwide
Run by
Sanofi
See details and how to joinNCT07457580
Phase 3Taking people
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults
Where
Ancona, Bologna, Cagliari, Florence, Milan, Naples, Novara, Padova, Verona
Age
1 year to 35 years
People
150 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07222137 · EU 2025-521797-34-00
Phase 3Taking people
A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)
Where
Ancona, Florence, Messina, Milan, Naples, Novara, Padova, Verona
Age
1 year to 35 years
People
300 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07222332 · EU 2025-522170-36-00
No phaseTaking people
Differentiating Heart Disease Between Adult-onset Autoimmune and Type 2 Diabetes
Where
Rome
Age
30 years and over
People
200
Run by
University of Roma La Sapienza
See details and how to joinNCT07911007
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Where
Bologna, Milan, Palermo, Pisa, Rome, Rozzano, Sesto San Giovanni, Turin
Age
18 years and over
People
2,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784725 · EU 2025-523379-41-00
Phase 4Taking people
Anti-viral action against Type 1 diabetes autoimmunity GPPAD-05-AVAnT1A
Where
Milan
Age
Up to 17 years
People
2,365 worldwide
Run by
Klinikum rechts der Isar der TU Muenchen AöR
See details and how to join2023-507348-35-00 · EU 2023-507348-35-00
Phase 3Taking people
A Study to Investigate Efficacy and Safety of Teplizumab Compared With Placebo in Participants 1 to 25 Years of Age With Stage 3 Type 1 Diabetes
Where
Bologna, Florence, Genoa, Messina, Milan, Novara, Pescara, Rome, Siena, Turin, Verona
Age
1 year to 25 years
People
723 worldwide
Run by
Sanofi
See details and how to joinNCT07088068
Phase 2Taking people
SAFety and Efficacy of Human Anti-thymocyte ImmunoGlobUlin SAB-142 ARresting Progression of Type 1 Diabetes
Where
Milan, Novara, Verona
Age
5 years to 40 years
People
159 worldwide
Run by
SAb Biotherapeutics, Inc.
See details and how to joinNCT07187531 · EU 2025-521560-36-00
No phaseTaking people
Strategy For Assessing The Risk Of Type 1 Diabetes In Pediatric Celiac Patients
Where
Bari
Age
1 year to 18 years
People
600
Run by
University of Bari
See details and how to joinNCT07862101
Phase 3Taking people
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Ancona, Bologna, Brescia, Catanzaro, Genoa, Messina, Milan, Perugia, Pisa
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
Phase 3Taking people
A trial to learn how safe elecoglipron is and how well it works in adults living with obesity or excess body weight with or without type 2 diabetes
Where
Bologna, Catania, Chieti, Florence, Latina, Milan, Pisa, Ravenna, Rome, San Donato Milanese
Age
18 years and over
People
1,010 worldwide
Run by
AstraZeneca AB
See details and how to join2025-524688-19-00 · EU 2025-524688-19-00
Phase 3Taking people
A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes
Where
Milan
Age
18 years to 65 years
People
57 worldwide
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT04786262 · EU 2024-513929-23-00
Phase 3Taking people
AMBITION 7: A Research Study Investigating How Well Zenagamtide Lowers Blood Sugar and Body Weight Compared to Insulin Glargine in People With Type 2 Diabetes and Increased Risk of Diseases That Affect the Heart and Blood Vessels Treated With 1-3 Other Diabetes Medications
Where
Catanzaro, Chiavari, Chieti, Lucca, Milan, Naples, Ravenna, Roma
Age
45 years and over
People
1,778 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07797335
No phaseTaking people
INNODIA Family & Friends Early-Stage T1D Detection Protocol
Where
Milan
Age
1 year to 45 years
People
30,000 worldwide
Run by
INNODIA iVZW
See details and how to joinNCT07118098
No phaseNot yet taking people in Italy
Targeting GLUT1 to Control Autoimmunity in Type 1 Diabetes
Where
Milan
Age
18 years and over
People
84
Run by
IRCCS San Raffaele
See details and how to joinNCT07695727
No phaseNot yet taking people in Italy
M1no-Study - Early Identification of Infants With High Type 1 Diabetes Risk for Participation in Primary Prevention Trials
Where
Lecco, Milan, Novara, Varese
Age
0 weeks to 6 weeks
People
50,000
Run by
IRCCS San Raffaele
See details and how to joinNCT07670143
No phaseNot yet taking people in Italy
Evaluation of the Safety and Effectiveness of the Novel Medtronic Experimental Automated Insulin Delivery System (NMX8) in Adults Living With Type 1 Diabetes
Where
Bologna, Milan, Naples, Roma
Age
18 years and over
People
230 worldwide
Run by
Medtronic MiniMed, Inc.
See details and how to joinNCT07401901
No phaseNot yet taking people in Italy
Standardized Italian netwoRk Enrolling iNdividuals With Islet-Autoantibodies
Where
Ancona, Bari, Bolzano, Caserta, Catanzaro, Crotone, Florence, L’Aquila, Milan, Naples, Novara, Padova, Palermo, Parma, Pavia, Reggio Calabria, Roma, San Giovanni Rotondo, Taranto, Trento, Treviso, Trieste, Verona, Viterbo
People
300
Run by
Società Italiana di Endocrinologia e Diabetologia Pediatrica
See details and how to joinNCT07503366
No phaseTaking people
Evaluation of Oxidative Stress: Comparison Between Type 1 Diabetes Mellitus and Latent Autoimmune Diabetes in Adults
Where
Pavia
Age
18 years to 75 years
People
75
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT07434154
No phaseTaking people
Vey Low-Energy Ketogenic Therapy in Adults With Type 1 Diabetes and Obesity on Intensive Insulin Therapy Using Advanded Hybrid Closed Loop System
Where
Bari
Age
18 years to 99 years
People
14
Run by
Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
See details and how to joinNCT07185555
No phaseTaking people
Evaluation of Main Determinants of Postprandial Glucose Response in Type 1 Diabetes
Where
Naples
Age
18 years to 70 years
People
200
Run by
Federico II University
See details and how to joinNCT05936242
No phaseTaking people
TrialNet Pathway to Prevention of T1D
Where
Milan
Age
2 years to 45 years
People
75,000 worldwide
Run by
University of South Florida
See details and how to joinNCT00097292
No phaseTaking people
Real-world Study on the Effectiveness and Safety of Control-IQ Technology in Teenagers With Type 1 Diabetes Engaging in Regular Physical Activity
Where
Messina
Age
Up to 20 years
People
50
Run by
Bruno Bombaci
See details and how to joinNCT06876207
No phaseTaking people
Glycemic Response to Carbob-Enriched Pasta in Healthy and With Type 1 Diabetes People
Where
Naples
Age
18 years to 50 years
People
10
Run by
Federico II University
See details and how to joinNCT06994403
Phase 1/2Not yet taking people in Italy
A First-in-human Clinical Trial Using a Gene Therapy With Patient's Own Stem Cells to Treat Early Type 1 Diabetes
Where
Padova
Age
18 years to 40 years
People
15
Run by
Altheia Science
See details and how to joinNCT06938334 · EU 2025-521304-21-00