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TerminatedNo phase

Efficacy of Methimazole Dosing Algorithm

Reason given: Unable to reach recruiting goals

Key facts

Where
Chicago, United StatesSee the site

Where in United States

  • Cook County HealthChicago, United StatesNo longer taking part

Trial details

Who runs it
Cook County Health
Trial code
NCT05964452
Record updated
27 December 2024
Original description
To prospectively study the efficacy and safety of the Cook County Health (CCH) methimazole (MMI) dosing algorithm in the setting of new onset Graves' disease.Read full original descriptionShow less

The Efficacy of Cook County Health's Methimazole Dosing Algorithm in the Setting of Ne Onset Graves' Hyperthyroidism

To prospectively study the efficacy and safety of the Cook County Health (CCH) methimazole (MMI) dosing algorithm in the setting of new onset Graves' disease.

Inclusion: Non-pregnant adults (>18 years of age) with new diagnosis of Graves' Disease (elevated free T4, Free T3, low or suppressed TSH, positive TSI and or thyroid eye disease) and; either drug naïve or who have been initiated on MMI within previous 4-6 weeks per CCH algorithm.

Exclusion: Pregnant patients; hyperthyroidism due to other causes, example - Toxic Multinodular Goiter, Iodine induced thyrotoxicosis, etc; Graves patients who present with atrial fibrillation, CHF or other end organ damage.

ClinicalTrials.gov NCT05964452