Graves' disease and hyperthyroidism trials in United States

In United States 17 Also abroad 55

17 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Natural History of Thyroid Function Disorders
Where
Bethesda
Age
6 months to 98 years
People
2,500
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT00001159
Phase 3Taking people
Study to Determine if BHV-1300 is Effective and Safe in Adults With Graves' Disease
Where
Albuquerque, Amarillo, Asheville, Atlanta, Baton Rouge, Burbank, Canton, Champaign, Chattanooga, Cincinnati, Dallas, Denton, Doral, El Paso, Farmington Hills, Fayetteville, Fort Myers, Greenville, Hialeah, Hollywood, Houston, Huntington Beach, Kansas City, La Jolla, Las Vegas, Layton, Lenexa, McKinney, Memphis, Miami, Midlothian, Morehead City, Norman, North Charleston, Oak Brook, Oakland, Orchard Park, Palm Beach Gardens, Philadelphia, Raleigh, San Antonio, San Diego, Seattle, Shavano Park, South Gate, Springfield, Statesville, St Louis, Tampa, Tucson, Walnut Creek, Washington D.C., Weslaco, Wilmington
Age
18 years to 70 years
People
300 worldwide
Run by
Biohaven Therapeutics Ltd.
See details and how to joinNCT07661056 · EU 2026-526455-53-00
Phase 2Taking people
A Study to Learn About The Effects of Felzartamab on Thyroid Function and Its Safety in Adults With Graves' Disease Ages 18 to 75 Years Old
Where
Asheville, Dallas, Doral, Glendale, Hamilton, Hialeah, Houston, Humble, Los Angeles, Lutherville, Miami, Naperville, Richmond, San Jose
Age
18 years to 75 years
People
60 worldwide
Run by
Biogen
See details and how to joinNCT07722546 · EU 2026-526482-19-00
Phase 3Taking people
A Study to Assess Efficacy and Safety of Efgartigimod PH20 SC PFS in Adult Participants With Graves' Disease
Where
Albany, Ann Arbor, Asheville, Carlsbad, Dallas, Dearborn, El Paso, Farmington Hills, Fleming Island, Fort Lauderdale, Houston, Irving, Jacksonville, Kansas City, Kissimmee, Lenexa, McAllen, McKinney, Mesquite, Miami, New York, Orange, Pasadena, Raleigh, San Jose, Shavano Park, Wichita
Age
18 years and over
People
230 worldwide
Run by
argenx
See details and how to joinNCT07570316 · EU 2025-524223-42-00
Phase 2Taking people
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Where
Aurora, Chapel Hill, Columbus, Concord, Dallas, Doral, El Paso, Fort Worth, Hialeah, Hickory, Houston, Irving, Jefferson City, Kansas City, Long Island City, Louisville, McKinney, Memphis, Miami, Morehead City, New Hyde Park, New York, Norfolk, Oklahoma City, Raleigh, Reno, San Antonio, St Louis, Topeka, Tucson, Williamsville
Age
18 years to 75 years
People
210 worldwide
Run by
Immunovant Sciences GmbH
See details and how to joinNCT07018323 · EU 2025-521920-31-00
Phase 2Taking people
Evaluation of YB-101 for Safety, Tolerability, Pharmacokinetics, and Efficacy in Graves' Disease
Where
Amarillo, Bowling Green, Cary, Conroe, Dallas, Durham, Edinburg, El Paso, Flint, Fort Worth, Gilbert, Houston, Humble, La Mesa, Livonia, Macon, Miami Lakes, Niagara Falls, Ocoee, Omaha, Orchard Park, Palm Harbor, Phoenix, Sacramento, San Francisco, Sarasota, Sayre, Torrance, Tucson
Age
18 years and over
People
232 worldwide
Run by
Yarrow Bioscience, Inc.
See details and how to joinNCT07682896
Phase 1Taking people
NEXUS Study: A Study to Test Single and Multiple Doses of MER511 Given to Adults With Graves' Disease
Where
Boston, Columbus, DeSoto, Hollywood, Miami, Morehead City, Philadelphia, Rochester, Torrance, Webster, Wesley Chapel
Age
18 years to 65 years
People
100 worldwide
Run by
Merida Biosciences
See details and how to joinNCT07305818 · EU 2025-523823-23-00
Phase 1Taking people
Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye Disease
Where
Las Vegas, Orland Park, Wilmington
Age
18 years and over
People
72
Run by
Ethyreal Bio, Inc.
See details and how to joinNCT07885605
Phase 3Taking people
Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)
Where
Asheville, Beverly Hills, Canoga Park, Coral Gables, East Weymouth, Glendale, Houston, Jacksonville, Las Vegas, Livonia, Morgantown, New York, Norfolk, Pasadena, Reno, San Francisco, Santa Monica, Somerset
Age
18 years and over
People
130
Run by
Sling Therapeutics, Inc.
See details and how to joinNCT07753603
No phaseEnrolling by invitation
Pressure-enabled Retrograde Occlusive Therapy With Embolization for Control of Thyroid Disease (PROTECT Registry): A Multicenter Registry
Where
Atlanta, Jacksonville, New Orleans, Sarasota
Age
18 years to 89 years
People
100
Run by
Sarasota Memorial Health Care System
See details and how to joinNCT06868459
Phase 2Enrolling by invitation
A Long-Term Extension Study of IMVT-1402 in Adult Participants With Graves' Disease (GD)
Where
Asheville, Atlanta, Aurora, Austin, Baltimore, Bellaire, Boston, Bowling Green, Canton, Chapel Hill, Chattanooga, Clearwater, Columbus, Concord, Dallas, Doral, El Paso, Englewood, Farmington Hills, Flint, Florence, Fort Worth, Gulfport, Hialeah, Hickory, Houston, Huntington Beach, Indianapolis, Irving, Jacksonville, Jefferson City, Kansas City, Las Vegas, Los Angeles, Louisville, Macon, McKinney, Memphis, Mesquite, Metairie, Miami, Monroe, Morehead City, Nashville, Newark, New Hyde Park, New Orleans, New York, Norfolk, Ocoee, Oklahoma City, Omaha, Orange, Orlando, Philadelphia, Phoenix, Port Charlotte, Portland, Pottstown, Raleigh, Reno, Rochester, Round Rock, Salt Lake City, San Antonio, Sandy City, San Francisco, Santa Clarita, Stockbridge, Summerville, Topeka, Torrance, Tucson, Washington D.C., West Palm Beach, Williamsville, Wilmington
Age
18 years and over
People
372 worldwide
Run by
Immunovant Sciences GmbH
See details and how to joinNCT07286006
Phase 2Taking people
A Study to Assess the Efficacy, Safety, and Tolerability of IMVT-1402 as Treatment for Adult Participants With Graves' Disease
Where
Asheville, Atlanta, Austin, Baltimore, Bellaire, Boston, Bowling Green, Canton, Chattanooga, Clearwater, Dallas, Englewood, Farmington Hills, Flint, Florence, Gulfport, Houston, Huntington Beach, Indianapolis, Jacksonville, Kansas City, Las Vegas, Los Angeles, Macon, Mesquite, Metairie, Miami, Monroe, Nashville, Newark, New Orleans, Ocoee, Omaha, Orange, Orlando, Philadelphia, Phoenix, Port Charlotte, Portland, Pottstown, Rochester, Round Rock, Sacramento, Salt Lake City, San Antonio, Sandy City, San Francisco, Santa Clarita, Shreveport, Stockbridge, Summerville, Torrance, Walnut Creek, Washington D.C., West Palm Beach, Wilmington
Age
18 years to 75 years
People
240 worldwide
Run by
Immunovant Sciences GmbH
See details and how to joinNCT06727604 · EU 2024-516020-33-00
Phase 4Taking people
Preoperative Corticosteroids in Autoimmune Thyroid Disease
Where
Indianapolis
Age
18 years and over
People
76
Run by
Indiana University
See details and how to joinNCT05435547
Phase 1Taking people
Study of BHV-1300 in Graves' Disease
Where
Canton, Columbus, Dallas, Greenville, Houston, Memphis, Miami, Shavano Park, South Gate
Age
18 years to 65 years
People
15 worldwide
Run by
Biohaven Therapeutics Ltd.
See details and how to joinNCT06980649
No phaseTaking people
Telehealth Music Therapy for Adults With Endocrine Disorder and Depression
Where
Boone
Age
18 years to 65 years
People
10
Run by
Appalachian State University
See details and how to joinNCT07413874
No phaseTaking people
Evaluating an AI Tool for Detecting Thyrotoxic States
Where
San Francisco
Age
22 years and over
People
15
Run by
THYROSCOPE INC.
See details and how to joinNCT07017907
No phaseTaking people
The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction
Where
Bethesda
Age
18 years and over
People
100
Run by
Walter Reed National Military Medical Center
See details and how to joinNCT06275373