Records routine SIR-Spheres treatment in adults with inoperable liver tumors
Follows adults with liver cancer or colorectal cancer spread to the liver treated with SIR-Spheres.
Plain-language title generated from the registry record
Registry title: Observational SIR-Spheres Study for the Treatment of Unresectable Liver Tumors (SIRtain Registry)
Key facts
- Where
- Madrid, Majadahonda, and Valencia, SpainSee the 3 sites
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with liver cancer (hepatocellular carcinoma) or colorectal cancer that spread to the liver, which surgery cannot remove, who are about to get SIR-Spheres treatment for the first time.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Unresectable hepatocellular carcinoma (HCC), or unresectable liver metastases from colorectal cancer (mCRC) that did not respond to chemotherapy or could not be treated with it
- Earlier treatment
- Must not have had radiation treatment to the liver before; must be planned to get SIR-Spheres treatment to the liver for the first time
Main reasons for not taking part
- Earlier radiation treatment to the liver
- Taking part in another interventional clinical trial with an investigational product, device or procedure
- Cannot give consent for themselves
Read by machine on 12 November 2026.
Where in Spain
- Hospital General Universitario Gregorio MarañónMadrid, SpainContact: Pilar Garcia Alfonso (principal investigator)Not yet recruiting
- Hospital Universitario Puerta de Hierro - MajadahondaMajadahonda, SpainContact: Lourdes Gutierrez (principal investigator)Not yet recruiting
- Hospital Clinico Universitario de ValenciaValencia, SpainContact: Paloma Lluch (principal investigator)Not yet recruiting
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Sirtex Medical
- Trial code
- NCT05967143
- Record updated
- 27 November 2024
- Original description
This registry seeks to prospectively gather a large repository of comprehensive observational data reflecting routine use of SIR-Spheres in patients diagnosed with unresectable HCC or unresectable liver metastases from mCRC refractory to or intolerant to chemotherapy, in order to assess clinical response in a real-world setting and further validate the safe and appropriate use of SIR-SpheresRead full original descriptionShow less
Observational Study to Assess Real-World Outcomes in Patients With Unresectable Liver Tumors Initiating Treatment With SIR-Spheres (Y-90 Resin Microspheres) (SIRtain Registry)
This registry seeks to prospectively gather a large repository of comprehensive observational data reflecting routine use of SIR-Spheres in patients diagnosed with unresectable HCC or unresectable liver metastases from mCRC refractory to or intolerant to chemotherapy, in order to assess clinical response in a real-world setting and further validate the safe and appropriate use of SIR-Spheres
Inclusion: Age 18 years or older; Confirmed diagnosis of:; Unresectable hepatocellular carcinoma (HCC) Or; Unresectable liver metastases from colorectal cancer (mCRC) refractory to or intolerant to chemotherapy; Identified as a candidate for SIR-Spheres treatment as deemed appropriate during the normal course of practice; Planned to receive SIR-Spheres treatment to the liver for the first time; Provision of signed patient informed consent.
Exclusion: Prior radiation treatment to the liver; Caveat:; Sequential selective internal radiation therapy (SIRT) treatment is allowed; Patients participating in any interventional clinical trial with an investigational product, device, or procedure; Need for surrogate consent. Patients who are not able to consent on behalf of themselves are not eligible.