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Studies immune problems linked to clonal hematopoiesis and VEXAS syndrome

Observes adults with immune and inflammatory conditions, with or without clonal hematopoiesis.

Plain-language title generated from the registry record
Registry title: Clonal Hematopoiesis of Immunological Significance

Key facts

Where
Paris, FranceSee the site

Where in France

  • AP-HP, Service de médecine interne, Hôpital Saint AntoineParis, FranceNo longer taking part

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Trial details

Who runs it
Assistance Publique - Hôpitaux de Paris
Trial code
NCT05969821
Record updated
23 March 2026
Original description
Ambispective, national, multicenter observational cohort study aimed at characterizing the satellite dysimmune manifestations of clonal hematopoiesis, including Vexas (Vacuoles, E1 enzyme, X-linked, Autoinflammatory and Somatic) syndrome.Read full original descriptionShow less

Immuno-inflammatory Manifestations With or Without Clonal Hematopoiesis: Ambispective Cohort Study

Ambispective, national, multicenter observational cohort study aimed at characterizing the satellite dysimmune manifestations of clonal hematopoiesis, including Vexas (Vacuoles, E1 enzyme, X-linked, Autoinflammatory and Somatic) syndrome.

Inclusion: Age >=18 years old; Confirmed dysimmune manifestations: clinical or biological abnormality or systemic disease; Presence or absence of myeloid or lymphoid blood disease according to World Health Organization (WHO) classification.

Exclusion: Persons benefiting from special protection: adults under guardianship and curatorship; People hospitalized without their consent and not protected by law; persons deprived of liberty; Persons not affiliated to the social security system.

ClinicalTrials.gov NCT05969821