Tests two online non-drug programs for adults with migraine
Compares two virtual, non-drug programs for adults with migraine headaches.
Plain-language title generated from the registry record
Registry title: BE WELL With Migraine: Brain Education and WELLness With Migraine
Key facts
- Where
- Cambridge, Cincinnati, and Winston-Salem, United StatesSee the 3 sites
Where in United States
- Cambridge Health Alliance - Center for Mindfulness and CompassionCambridge, United StatesNot yet recruiting
- Cincinnati Children's Hospital Medical CenterCincinnati, United StatesNot yet recruiting
- Wake Forest University Health SciencesWinston-Salem, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Wake Forest University Health Sciences
- Trial code
- NCT05987592
- Record updated
- 12 June 2026
- Original description
The goal of this randomized clinical trial is to evaluate two different non-drug, virtual treatment options designed to improve the lives of patients with migraine. Both interventions involve 8 weekly sessions and an online platform with additional content and learning. Participants can stay on all their medications during this study. Information from this study may help determine how to better treat migraine.Read full original descriptionShow less
BE WELL With Migraine: Brain Education and WELLness With Migraine
The goal of this randomized clinical trial is to evaluate two different non-drug, virtual treatment options designed to improve the lives of patients with migraine. Both interventions involve 8 weekly sessions and an online platform with additional content and learning. Participants can stay on all their medications during this study. Information from this study may help determine how to better treat migraine.
Inclusion: Diagnosis of migraine with or without aura by with headache frequency of 4-20 days/month; At least 1 year of migraine; At least 18 years old; Able to participate in 8 weekly online classes; Willingness to complete baseline headache logs; Headache-related disability (Headache Impact Test (HIT)-6) score >50; Fluent in English; Completion of technology onboarding with the online platform; Pregnant women who are less than or equal to 16 weeks gestation at enrollment are allowed to participate.
Exclusion: Medication overuse headache, with migraine treatment; Unstable migraine treatment at enrollment: any preventive treatment (oral or injectable medication or neuromodulatory device) started within 12 weeks OR acute treatment within 4 weeks to ensure stability; Unwillingness to maintain stable current medication dosages for study duration; Heavy alcohol and illicit drug use; Experience with stress reduction training (daily meditation practice, regular use of a mindfulness app, or prior experience with MBSR); Major unstable medical/psychiatric condition that could be unsafe for participants or for the group environment; Failure to complete baseline headache logs; Any, and all other diagnoses or conditions which, in the opinion of the site investigator, would prevent the patient from being a suitable candidate for the study or interfere with the medical care needs of the study participant: COVID-positive test within 30 days of enrollment; Pregnant women who are more than 16 weeks gestation at enrollment; Participation in another intervention clinical trial or one that would interfere in this study.