CompletedNo phase
Cereset Research Long-Term Healthcare Worker Study
Key facts
- Who runs it
- Wake Forest University Health Sciences
- Where
- Winston-Salem, United StatesSee the site
- Trial code
- Status
- Completed
- People taking part
- 94 people enrolled
- Started
- 6 Nov 2023
- Ended
- 1 Jul 2025
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Cereset Research
- Record updated
- 21 September 2026
Who can take part
- Age
- 18 years to 100 years
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 15 criteriaShow less
Who can take part
- Employed healthcare workers aged 18 years and older
- Have availability and interest in participating in a 1 year study
- Ability to comply with basic instructions and be able to sit still, comfortably during sessions
- Experiencing symptoms of stress meeting threshold score on the Perceived Stress Scale (PSS ≥ 14)
Who cannot take part
- Prior use of: HIRREM, HIRREM-SOP, Brainwave Optimization (BWO), Cereset, Cereset Research, Cereset Home, or a wearable configuration of the same (B2, or B2v2)
- Prior use of the following modalities within one month before enrollment: electroconvulsive therapy (ECT), prior use of transcranial magnetic stimulation (TMS), transcranial direct current stimulation (TDCS), alpha stimulation, eye movement desensitization and reprocessing (EMDR), brain spotting, neurofeedback, biofeedback, or deep brain stimulation (DBS)
- Severe hearing impairment (because the subject will be using ear buds during CR)
- Known seizure disorder
- No internet access, as some visits collected electronically
- Unable, unwilling, or incompetent to provide informed consent
- Physically unable to come to the study visits, or to sit still, comfortably in a chair for up to 1 hour
- Weight is over the chair limit (400 pounds)
- Currently enrolled in another active intervention research study
- Thoughts of active suicide within the last 3 months
- Current medical student
Where in United States
- Atrium Wake Forest Baptist HealthWinston-Salem, United StatesNo longer taking part
About the trial
What the trial wants to find out
Randomized, controlled study of long-term maintenance Cereset Research after an initial 4-session intervention bolus versus usual care control following an initial 4-session intervention bolus.
The 2 groups in the trial
- Cereset Research Tune-Up Intervention GroupExisting treatment, for comparison
All study participants will receive 4 initial CR sessions. Afterwards, they will be randomized, and this group will receive an additional tune-up (maintenance) session every 6 weeks for one year. There will be a CR session at weeks 6, 12, 18, 24, 30, 36, 42, and 48.
Treatment: Cereset Research
- Cereset Research Control GroupOther group
All study participants will receive 4 initial CR sessions. Afterwards, they will be randomized, and this group will continue their current care for 1 year with no additional CR sessions.
Treatment: Cereset Research
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Evaluating Long-Term Feasibility of Cereset Research for Stressed Healthcare Workers
- Record updated
- 21 September 2026