Insomnia trials in United States

In United States 126 Also abroad 347

126 trials · From ClinicalTrials.gov, checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Enhancing Hypnotic Medication Discontinuation in Primary Care
Where
Denver
Age
18 years and over
People
250
Run by
National Jewish Health
See details and how to joinNCT06435520
Phase 4Taking people
The Role of mGluR5 in CBT-I
Where
Stony Brook
Age
18 years and over
People
42
Run by
Stony Brook University
See details and how to joinNCT07076342
No phaseNot yet taking people in United States
Scheduled Meditation for Improving Postoperative Outcomes in Patients Undergoing Pancreatectomy
Where
Duarte
Age
18 years and over
People
70
Run by
City of Hope Medical Center
See details and how to joinNCT07608458
Phase 2Not yet taking people in United States
A Study of Oral SOM001 as a Safe and Effective Treatment for Adults With Chronic Insomnia
Where
New York
Age
18 years to 65 years
People
45
Run by
Somnum Pharma Inc.
See details and how to joinNCT07920185
No phaseNot yet taking people in United States
SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment
Where
San Diego
Age
60 years and over
People
150
Run by
VA Office of Research and Development
See details and how to joinNCT07397182
No phaseNot yet taking people in United States
A Transdiagnostic Sleep Health Intervention for Veterans With PTSD
Where
San Francisco
Age
18 years and over
People
182
Run by
VA Office of Research and Development
See details and how to joinNCT06549049
No phaseTaking people
Evaluation of Cognitive Behavioral Therapy for Insomnia (CBT-I) in Individuals With Mild Traumatic Brain Injury (mTBI)
Where
Columbia
Age
18 years to 60 years
People
15
Run by
University of Missouri-Columbia
See details and how to joinNCT07385105
No phaseTaking people
Addressing Nocturia in Older Women Utilizing Behavioral Sleep Intervention and Brief Mindfulness
Where
Pittsburgh
Age
65 years and over
People
80
Run by
University of Pittsburgh
See details and how to joinNCT07760779
No phaseTaking people
Treating Insomnia in Mild Cognitive Impairment
Where
Boston
Age
60 years and over
People
30
Run by
Beth Israel Deaconess Medical Center
See details and how to joinNCT06687161
Phase 4Taking people
The Effects of Orexin Antagonism on Fear Extinction in PTSD
Where
Charleston, San Francisco
Age
18 years to 75 years
People
40,120
Run by
VA Office of Research and Development
See details and how to joinNCT06788522
Phase 3Taking people
A Trial to See if Daridorexant Can Help Adults and Elderly People With Insomnia Sleep Better During the Night and Function Better During the Day
Where
Brandon, Cincinnati, Huntersville, Lemon Grove, Little Rock, Pomona, Raleigh, Virginia Gardens, Weston
Age
18 years and over
People
344
Run by
Idorsia Pharmaceuticals Ltd.
See details and how to joinNCT07843329 · EU 2026-525730-38-00
No phaseNot yet taking people in United States
Deaf CBT-TS to Reduce Suicide Risk
Where
Rochester
Age
18 years and over
People
110
Run by
University of Rochester
See details and how to joinNCT07279363
Phase 3Taking people
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
Where
Anaheim, Atlanta, Austin, Avon Lake, Bellaire, Birmingham, Boston, Brandon, Brooklyn, Bryant, Buffalo, Chandler, Charleston, Chicago, Cincinnati, Colton, Columbus, Dallas, Decatur, Denver, Draper, Dunwoody, Edmond, Elgin, Encino, Everett, Farmington, Fort Worth, Garland, Glendale, Hialeah, Hickory, Homestead, Houston, Jacksonville, Lake City, Largo, Las Vegas, Little Rock, Los Alamitos, Mankato, Miami, Middleburg Heights, Mount Kisco, Naperville, Naples, New York, North Bay Village, Oceanside, Orlando, Philadelphia, Portsmouth, Rancho Cucamonga, Redlands, Saint Augustine, San Jose, Santa Ana, Savannah, Sherman Oaks, Snellville, Stafford, Tampa, Tucson, Watertown, West Palm Beach, Wichita Falls, Winter Park, Woodbury
Age
18 years to 74 years
People
752 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06559306 · EU 2023-509070-36-00
No phaseTaking people
Restorative Early Sleep Treatment After the Emergency Department
Where
Detroit
Age
18 years and over
People
80
Run by
Henry Ford Health System
See details and how to joinNCT07121270
No phaseTaking people
The Effect of a Daily Magnesium and Melatonin Supplement on Sleep Quality in People With Nighttime Leg Cramps
Where
Atlanta, Birmingham, Charleston, Charlotte, Little Rock, Nashville, Palm Beach Gardens
Age
40 years to 75 years
People
50
Run by
StudySetGo
See details and how to joinNCT07651514
No phaseNot yet taking people in United States
HALO Clarity™ Cranial Alternating Current Stimulation Therapy for Adults With Moderate-to-Severe Insomnia
Where
Houston
Age
22 years to 65 years
People
160
Run by
Nexalin Technology
See details and how to joinNCT07659366
No phaseTaking people
Assessing the Feasibility of Web-based Insomnia Treatment Among Prostate Cancer Survivors
Where
Washington D.C.
Age
21 years and over
People
40
Run by
Georgetown University
See details and how to joinNCT07128927
No phaseTaking people
DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer
Where
Basking Ridge, Commack, Harrison, Middletown, Montvale, New York, Rockville Centre
Age
21 years to 100 years
People
125 worldwide
Run by
Ponce Medical School Foundation, Inc.
See details and how to joinNCT07225088
No phaseNot yet taking people in United States
Sleep MAPP in the Polytrauma/TBI System of Care
Where
Aurora, Tampa
Age
18 years and over
People
900
Run by
VA Office of Research and Development
See details and how to joinNCT07886398
Phase 2Taking people
Deep Sleep in Older Adults
Where
New York
Age
55 years and over
People
180
Run by
Proactive Life Inc
See details and how to joinNCT07316153
Phase 1Taking people
PrP-targeting siRNA Safety & Mechanism Study
Where
Boston, Cleveland, Nashville, New York, Rochester
Age
18 years and over
People
45
Run by
Broad Institute of MIT and Harvard
See details and how to joinNCT07444580
Phase 2Taking people
Suvorexant for Treatment of AUD and PTSD
Where
Houston, Los Angeles
Age
21 years to 65 years
People
76
Run by
Pharmacotherapies for Alcohol and Substance Use Disorders Alliance
See details and how to joinNCT06679062
No phaseTaking people
Insomnia Behavioral Intervention Study
Where
Philadelphia
Age
55 years to 85 years
People
20
Run by
University of Pennsylvania
See details and how to joinNCT05301543
Phase 2Taking people
Comparing Telehealth-Delivered CBT-I to Web-Based CBT-I to Enhance Sleep, Reduce Fatigue, and Promote Neuroprotection
Where
Kansas City
Age
18 years to 65 years
People
90
Run by
University of Kansas Medical Center
See details and how to joinNCT06434571
No phaseNot yet taking people in United States
Transcendental Meditation Intervention to Reduce Burnout and Enhance Resilience Among NewYork-Presbyterian Hospital and Weill Cornell Medicine Employees and Residents
Where
New York
Age
18 years and over
People
15
Run by
Weill Medical College of Cornell University
See details and how to joinNCT07868783