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Taking people in JapanNo phase

Studies upadacitinib use and side effects in Crohn's disease patients in Japan

Follows people with Crohn's disease who are prescribed upadacitinib in routine care.

Plain-language title generated from the registry record
Registry title: An Observational Study to Assess Change in Disease Activity and Adverse Events in Adolescent and Adult Participants With Moderate to Severe Active Crohn's Disease (CD) in Japan

Key facts

Where
Ageo, Ako, Anjo-shi, Bunkyo-ku, Chikushino-shi, Chuo-ku, Fukui, Fukuoka, Fukushima, Fukuyama-shi, Gifu, Ginowan-shi, Hachinohe, Hamamatsu, Handa, Hatsukaichi, Himeji, Himeji-shi, Hiroshima, Ibaraki-shi, Isehara, Itami, Kagoshima, Kakamigahara-shi, Kamakura-shi, Kanazawa, Kashiwa-shi, Kawagoe, Kitakyushu, Kitakyushu-shi, Kobe, Kochi, Kofu, Koganei-shi, Kōriyama, Kumamoto, Kurume, Kurume-shi, Kyoto, Matsuyama, Mibu, Minato-ku, Moriguchi, Nagakute, Nagano, Nagasaki, Nagoya, Naha, Nishinomiya-shi, Odawara-shi, Ōita, Onga-gun, Ono, Osaka, Saga, Sagamihara-shi, Saitama, Saitama-shi, Sakai, Sapporo, Setagaya-ku, Shibuya-ku, Shinjuku-ku, Shizuoka, Sizuoka-shi, Sumida-ku, Sunto-gun, Takamatsu, Takatsuki, Tokorozawa, Tokyo, Toyama, Toyohashi, Toyonaka, Toyota-shi, Tsu, Tsukuba, Ube, Utsunomiya, Uwajima, Wakayama, Yamagata, Yamaguchi, Yokkaichi-shi, and Yokohama, JapanSee the 104 sites

Where in Japan

  • Ohmori Toshihide Gastrointestinal Clinic /ID# 276192Ageo, JapanTaking people
  • Ako-City Hospital /ID# 271276Ako, JapanTaking people
  • Anjou Kousei Hospital /ID# 261872Anjo-shi, JapanTaking people
  • Juntendo University Hospital /ID# 265452Bunkyo-ku, JapanTaking people
  • Fukuoka University Chikushi Hospital /ID# 262686Chikushino-shi, JapanTaking people
  • Ginza Central Clinic /ID# 261881Chuo-ku, JapanTaking people
  • Fukuiken Saiseikai Hospital /ID# 274835Fukui, JapanTaking people
  • Sakemi clinic /ID# 275589Fukuoka, JapanTaking people
  • Fukushima Red Cross Hospital /ID# 275322Fukushima, JapanTaking people
  • National Hospital Organization Fukuyama Medical Center /ID# 261873Fukuyama-shi, JapanTaking people
  • Gifu University Hospital /ID# 266711Gifu, JapanTaking people
  • University of the Ryukyus Hospital /ID# 264430Ginowan-shi, JapanTaking people
  • Hachinohe City Hospital /ID# 264183Hachinohe, JapanTaking people
  • Kato Clinic /ID# 262650Hamamatsu, JapanTaking people
  • Handa City Hospital /ID# 270446Handa, JapanTaking people
  • JA Hiroshima General Hospital /ID# 264432Hatsukaichi, JapanTaking people
  • Himeji Chuo Hospital /ID# 272714Himeji, JapanTaking people
  • Japanease Red Cross Society Himeji Hospital /ID# 275590Himeji, JapanTaking people
  • Hyogo Prefectural Harima-Himeji General Medical Center /ID# 274528Himeji-shi, JapanTaking people
  • Kaisei Clinic /ID# 261883Hiroshima, JapanTaking people
  • Seshimo Gastroy & Procto Clinic /ID# 271658Ibaraki-shi, JapanTaking people
  • Tokai University Hospital /ID# 270949Isehara, JapanTaking people
  • Itami City Hospital /ID# 276258Itami, JapanTaking people
  • Kagoshima IBD Gastroenterology Clinic /ID# 265505Kagoshima, JapanTaking people
  • Sakura Clinic /ID# 268344Kakamigahara-shi, JapanTaking people
  • Gokeikai Ofuna Chuo Hospital /ID# 262649Kamakura-shi, JapanTaking people
  • National Hospital Organization Kanazawa Medical Center /ID# 268820Kanazawa, JapanTaking people
  • Tsujinaka Hospital - Kashiwanoha /ID# 262648Kashiwa-shi, JapanTaking people
  • Saitama Medical Center /ID# 270948Kawagoe, JapanTaking people
  • Steel Memorial Yahata Hospital /ID# 272713Kitakyushu, JapanTaking people
  • Tobata Kyoritsu Hospital /ID# 273558Kitakyushu, JapanTaking people
  • Kitakyushu Municipal Medical Center /ID# 276257Kitakyushu-shi, JapanTaking people
  • Aoyama Clinic /ID# 262658Kobe, JapanTaking people
  • Kobe City Medical Center General Hospital /ID# 270950Kobe, JapanTaking people
  • Chikamori Hospital /ID# 267382Kochi, JapanTaking people
  • Kuniyoshi Hospital /ID# 271878Kochi, JapanTaking people
  • Yamanashi Prefectural Central Hospital /ID# 274526Kofu, JapanTaking people
  • Koganei Tsurukame Clinic /ID# 271660Koganei-shi, JapanTaking people
  • Southern Tohoku General Hospital /ID# 270447Kōriyama, JapanTaking people
  • Coloproctology Center Takano Hospital /ID# 268868Kumamoto, JapanTaking people
  • Hidaka Colon Proctology Clinic /ID# 268867Kurume, JapanTaking people
  • Hakuai Clinic /ID# 261876Kurume-shi, JapanTaking people
  • Japanese Red Cross Kyoto Daiichi Hosital /ID# 262660Kyoto, JapanTaking people
  • National Hospital Organization Kyoto Medical Center /ID# 265461Kyoto, JapanTaking people
  • Matsuyama Red Cross Hospital /ID# 266717Matsuyama, JapanTaking people
  • Dokkyo Medical University Hospital /ID# 266710Mibu, JapanTaking people
  • Kitasato University Kitasato Institute Hospital /ID# 268345Minato-ku, JapanTaking people
  • Moriguchi Keijinkai Hospital /ID# 268821Moriguchi, JapanTaking people
  • Aichi Medical University Hospital /ID# 261871Nagakute, JapanTaking people
  • Nagano Municipal Hospital /ID# 262627Nagano, JapanTaking people
  • Honda Internal Medicine and Endoscopy Clinic /ID# 275628Nagasaki, JapanTaking people
  • Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital /ID# 276219Nagoya, JapanTaking people
  • Masuko Memorial Hospital /ID# 267420Nagoya, JapanTaking people
  • Nagoya City University Hospital /ID# 275588Nagoya, JapanTaking people
  • Naha City Hospital /ID# 261875Naha, JapanTaking people
  • Hyogo Medical University Hospital /ID# 267383Nishinomiya-shi, JapanTaking people
  • Shimizuogimachi Clinic /ID# 276278Odawara-shi, JapanTaking people
  • Ishida Clinic of IBD and Gastroenterology /ID# 261884Ōita, JapanTaking people
  • Ashiya Central Hospital /ID# 275324Onga-gun, JapanTaking people
  • Kita-Harima Medical Center /ID# 276256Ono, JapanTaking people
  • Kinshukai Infusion Clinic /ID# 261332Osaka, JapanTaking people
  • National Hospital Organization Osaka National Hospital /ID# 264230Osaka, JapanTaking people
  • Osaka Metropolitan University Hospital /ID# 273559Osaka, JapanTaking people
  • Tane General Hospital /ID# 268871Osaka, JapanTaking people
  • Saga-Ken Medical Centre Koseikan /ID# 274957Saga, JapanTaking people
  • Kitasato University Hospital /ID# 276524Sagamihara-shi, JapanTaking people
  • Saitama City Hospital /ID# 266716Saitama, JapanTaking people
  • Tokitokai Tokito clinic /ID# 262661Saitama-shi, JapanTaking people
  • Osaka Rosai Hospital /ID# 267379Sakai, JapanTaking people
  • Sapporo Ibd Clinic /ID# 281896Sapporo, JapanTaking people
  • Sapporo Kosei General Hospital /ID# 267374Sapporo, JapanTaking people
  • Ohori IBD Clinic /ID# 261882Setagaya-ku, JapanTaking people
  • Shinjuku Tsurukame Clinic /ID# 276485Shibuya-ku, JapanTaking people
  • Tokyo Medical University Hospital /ID# 262683Shinjuku-ku, JapanTaking people
  • Tokyo Women's Medical University Hospital /ID# 274527Shinjuku-ku, JapanTaking people
  • Shizuoka Aoi Clinic /ID# 267376Shizuoka, JapanTaking people
  • Saigusa Clinic Of Coloproctolo /ID# 275627Sizuoka-shi, JapanTaking people
  • Fraternity Memorial Hospital /ID# 274976Sumida-ku, JapanTaking people
  • NHO Shizuoka Medical Center /ID# 275551Sunto-gun, JapanTaking people
  • Maeda Hospital /ID# 275554Takamatsu, JapanTaking people
  • Takamatsu Red Cross Hospital /ID# 268823Takamatsu, JapanTaking people
  • Fujita Gastroenterology Hospital /ID# 275410Takatsuki, JapanTaking people
  • Tokorozawa Proctogic Hospital /ID# 268870Tokorozawa, JapanTaking people
  • Teikyo University Hospital /ID# 274525Tokyo, JapanTaking people
  • Teikyo University Hospital /ID# 274977Tokyo, JapanTaking people
  • Tokyo Yamate Medical Center /ID# 275591Tokyo, JapanTaking people
  • Yokota Memorial Hospital /ID# 266714Toyama, JapanTaking people
  • Toyohashi Municipal Hospital /ID# 274975Toyohashi, JapanTaking people
  • Municipal Toyonaka Hospital /ID# 266712Toyonaka, JapanTaking people
  • Ieda Hospital /ID# 259754Toyota-shi, JapanTaking people
  • Mie University Hospital /ID# 262656Tsu, JapanTaking people
  • Tsukuba Endoscopy clinic /ID# 261880Tsukuba, JapanTaking people
  • Sentohill Hospital /ID# 268869Ube, JapanTaking people
  • Saiseikai Utsunomiya Hospital /ID# 261878Utsunomiya, JapanTaking people
  • Uwajima City Hospital /ID# 273444Uwajima, JapanTaking people
  • Japanese Red Cross Wakayama Medical Center /ID# 268822Wakayama, JapanTaking people
  • Wakayama Medical University Hospital /ID# 262685Wakayama, JapanTaking people
  • Yamagata Prefectural Central Hospital - Yamagata /ID# 268819Yamagata, JapanTaking people
  • Yamaguchi Red Cross Hospital /ID# 267381Yamaguchi, JapanTaking people
  • Yokkaichi Hazu Medical Center /ID# 260140Yokkaichi-shi, JapanTaking people
  • Inoue Gastroenterology Clinic /ID# 275555Yokohama, JapanTaking people
  • Matsushima Hospital /ID# 276486Yokohama, JapanTaking people
  • Saiseikai Yokohama Tobu Hospital /ID# 264186Yokohama, JapanTaking people
  • Yokohama Municipal Citizen's Hospital /ID# 267375Yokohama, JapanTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
AbbVie
Trial code
NCT06023030
Record updated
24 February 2026
Original description
Crohn's disease (CD) is an incurable chronic inflammatory disorder of the gastrointestinal tract. This study will assess how safe and effective upadacitinib is in treating moderately to severely active CD in real world. Adverse events and change in disease activity will be assessed.Read full original descriptionShow less

A Post-marketing Non-interventional Study for Upadacitinib in Patients With Moderately to Severely Active Crohn's Disease (CD) in Japan

Crohn's disease (CD) is an incurable chronic inflammatory disorder of the gastrointestinal tract. This study will assess how safe and effective upadacitinib is in treating moderately to severely active CD in real world. Adverse events and change in disease activity will be assessed.

Upadacitinib is a drug approved for the treatment of CD. All study participants will receive upadacitinib as prescribed by their study doctor in accordance with approved local label. Approximately 240 participants will be enrolled in Japan.

Participants will receive upadacitinib as prescribed by their physician according to their routine clinical practice and local label. Participants will be followed for up to 64 weeks.

There is expected to be no additional burden for participants in this trial. Study visits may be conducted on-site or virtually as per standard of care.

Inclusion: Diagnosed with moderately to severely active Crohn's disease (CD); Has been prescribed upadacitinib for CD as per most current local approved label after its approval for CD in Japan; Within 14 days from the commencement of upadacitinib induction treatment for CD at the participating institution.

Exclusion: Has been treated with upadacitinib for CD before and continue treatment with upadacitinib for CD at the participation to this study; Currently participating in another interventional clinical research; Participants for whom upadacitinib is contraindicated.

ClinicalTrials.gov NCT06023030