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Immune Cell Signals in Allergic Asthma Patients

Studies immune cell signals that may distinguish allergic asthma from non-allergic disease in adults.

Plain-language title generated from the registry record
Registry title: Innate Immunity in Allergic Asthma

Key facts

Where
Orlando, United StatesSee the site

Where in United States

  • University of Central FloridaOrlando, United StatesTaking people

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Trial details

Who runs it
University of Central Florida
Trial code
NCT06068335
Record updated
6 December 2024
Original description
The purpose of this study is to determine whether a potential type 2 signature, obtained through stimulation of cell lines with various allergens in vitro, correlates with an allergic or asthmatic disease state ex vivo. This type 2 signature will be multi-hierarchical in nature and will be comprised cell surface receptor expression, pathway activation, and gene upregulation.Read full original descriptionShow less

Innate Immunity in Allergic Asthma

The purpose of this study is to determine whether a potential type 2 signature, obtained through stimulation of cell lines with various allergens in vitro, correlates with an allergic or asthmatic disease state ex vivo. This type 2 signature will be multi-hierarchical in nature and will be comprised cell surface receptor expression, pathway activation, and gene upregulation.

Inclusion: Participants must be at least 18 years of age; no history of allergic disease (healthy controls), have clinically diagnosed allergies, or have clinically diagnosed asthma.

Exclusion: Individuals currently suffering from any acute infections and those known to suffer from light-headedness will be excluded; Pregnant women and prisoners will be excluded from the study.

ClinicalTrials.gov NCT06068335