Asthma trials in United States

In United States 148 Also abroad 500

148 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Role of Genetic Factors in the Development of Lung Disease
Where
Bethesda
Age
2 years to 90 years
People
3,500
Run by
National Heart, Lung, and Blood Institute (NHLBI)
See details and how to joinNCT00001532
Phase 1Taking people
Pilot Study to Identify the Mediators and Inflammatory Cell Surface Receptors Involved in Allergic Airway Inflammation
Where
Boston
Age
18 years to 50 years
People
313
Run by
Benjamin Medoff
See details and how to joinNCT00595491
Phase 2Taking people
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
Where
Ann Arbor, Boerne, Champaign, Chandler, Charlotte, Colorado Springs, Cypress, Dallas, DuBois, East Point, Edmond, Gastonia, Henderson, Hendersonville, Houston, Huntersville, Kansas City, Lancaster, McKinney, Mobile, New Brunswick, Newport Beach, Northridge, Oklahoma City, Richmond, Riverdale, Rock Hill, San Jose, St Louis, Toledo, Tulsa, Walnut Creek
Age
18 years to 75 years
People
252 worldwide
Run by
Pfizer
See details and how to joinNCT06977581 · EU 2024-517866-40-00
Phase 2Taking people
A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
Where
Boston, Colorado Springs, Doral, Kirkland, Las Vegas, Nashville, Newport Beach, New York, Northridge, Ocala, Owensboro, Pensacola, Pittsburgh, Rolling Hills Estates, Tampa, Tempe, Westchester
Age
18 years to 75 years
People
531 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07219173
Phase 4Taking people
A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice
Where
Altamonte Springs, Ann Arbor, Asheville, Bellingham, Bessemer, Boca Raton, Brandon, California City, Chandler, Chicago, Columbia, Columbus, Cortland, Dallas, El Paso, Gastonia, Greenacres City, Greenville, Houston, Hurst, La Palma, Lexington, Lima, Los Angeles, Mesa, Miami, Miami Gardens, Miami Lakes, Missoula, Newport Beach, New Windsor, New York, North Miami Beach, Palm Springs, Papillion, Pasadena, Pittsburgh, Plantation, Port Saint Lucie, Rock Hill, Rockville, Scottsdale, Sewell, Sun City, Tamarac, Tampa, Tarzana, Tennessee City, Toledo, Tomball, Walnut Creek, West Palm Beach
Age
6 years and over
People
2,500 worldwide
Run by
Sanofi
See details and how to joinNCT07556159 · EU 2025-524916-13-00
Phase 3Taking people
A Study to Compare Safety of 4 Weeks Exposure to Propellants Hydrofluoroalkane 1,1-difluoroethane (HFA-152a) and HFA-1,1,1,2-tetrafluoroethane (134a)
Where
Aventura, Columbia, Cypress, Henderson, Medford, Miami, Naples, Owensboro, Spartanburg, Tomball
Age
18 years and over
People
110 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07645248
Phase 4Not yet taking people in United States
Novel Method for Removal of Orally Deposited Inhaled Fluticasone Propionate
Where
Madison
Age
18 years and over
People
20
Run by
University of Wisconsin, Madison
See details and how to joinNCT07664527
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of GSK5784283 Compared With Placebo in Participants With Uncontrolled Asthma (PERSIST ASTHMA-2)
Where
DuBois, Houston, Miami, Miami Lakes, San Diego, Tampa
Age
12 years to 80 years
People
370
Run by
GlaxoSmithKline
See details and how to joinNCT07782996
Phase 3Taking people
A Study to Learn About the Study Medicine Called Tilrekimig ( PF-07275315) in People With Severe Asthma
Where
Austin, Dallas, Edinburg, El Paso, Hannibal, McAllen, Oklahoma City, Pittsburgh, River Forest, The Bronx, Tomball
Age
12 years to 80 years
People
1,100 worldwide
Run by
Pfizer
See details and how to joinNCT07869043
No phaseNot yet taking people in United States
Reducing Exposure With Air Cleaners and Technology
Where
Berkeley, San Francisco
Age
13 years and over
People
100
Run by
University of California, Berkeley
See details and how to joinNCT07914010
No phaseNot yet taking people in United States
Asthma Ctrl SMART Trial
Where
Aurora, Cincinnati
Age
12 years to 18 years
People
389
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT07512622
Phase 2Taking people
Rademikibart IV for Acute Asthma and COPD Exacerbation
Where
Miami, St Louis
Age
18 years to 85 years
People
40
Run by
Connect Biopharm LLC
See details and how to joinNCT07705737
Phase 3Taking people
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)
Where
Bakersfield, Colchester, Dayton, Fall River, Houston, Inglewood, Kansas City, Lancaster, Miami, New York, Oklahoma City, Orlando, Rock Hill, San Antonio, Southfield, St Louis, Sugar Land, Tamarac, Tampa, West Covina, Williamsburg, Ypsilanti
Age
12 years to 80 years
People
786 worldwide
Run by
Generate Biomedicines
See details and how to joinNCT07359846
No phaseNot yet taking people in United States
Bilevel Positive Airway Pressure (BPAP) for Severe Asthma
Where
Columbus, New York, Philadelphia
Age
5 years to 17 years
People
36
Run by
Columbia University
See details and how to joinNCT07582211
Phase 1Taking people
A Study to Learn How Different Amounts of the Study Medicine Called PF-08103402 Are Tolerated and Act in the Body in Healthy Adults or Adults With Mild To-moderate Asthma
Where
New Haven
Age
18 years to 65 years
People
133 worldwide
Run by
Pfizer
See details and how to joinNCT07660731 · EU 2026-526260-21-00
No phaseNot yet taking people in United States
Artificially Intelligent Robot Control
Where
Miami
Age
4 years and over
People
80
Run by
University of Miami
See details and how to joinNCT07738016
Phase 2Taking people
A Study of JNJ-95597528 in Participants With Inadequately Controlled Moderate to Severe Asthma
Where
Boston, Edmond, Minneapolis, Oklahoma, St Louis, The Bronx, Westminster
Age
18 years to 85 years
People
440 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07746687 · EU 2026-526262-24-00
No phaseEnrolling by invitation
Firefighter's Longitudinal Airway and Respiratory Exposome/Multiome Study (FLARES)
Where
Bethesda
Age
18 years to 65 years
People
350
Run by
National Institute of Allergy and Infectious Diseases (NIAID)
See details and how to joinNCT07867184
Phase 2Taking people
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
Where
Asheville, Austin, Bakersfield, Bellevue, Bellingham, Boerne, Boise, Cutler Bay, Dallas, DuBois, Edmond, El Paso, Farmington Hills, Forney, Grand Island, Grants Pass, Greenville, Hialeah, Horseheads, Huntersville, Huntington Beach, Hutchinson, Kansas City, Kings Mountain, Kingwood, Knoxville, La Mesa, Leesburg, Loma Linda, Long Beach, Louisville, Maspeth, McKinney, Medford, Miami, Miami Lakes, Millville, Milwaukee, Mullica Hill, Newport Beach, Noblesville, Omaha, Orlando, Palmetto Bay, Philadelphia, Pinehurst, Portland, Rock Hill, Roy, San Jose, Smithfield, St Louis, Sugar Land, Tampa, Toledo, Toms River, Victoria, Warren, West Des Moines, White Marsh, Wilmington, Winter Park, Worcester
Age
18 years to 75 years
People
540 worldwide
Run by
AstraZeneca
See details and how to joinNCT06932263 · EU 2024-519116-14-00
Phase 3Taking people
A Study to Learn About the Study Medicine Called Tilrekimig in People With Severe Asthma
Where
Bakersfield, Baytown, Flint, Garland, Mesquite, Miami, Monroe, Smyrna, Southfield, Tulsa, Union City, Victoria, White Marsh
Age
12 years to 80 years
People
1,100 worldwide
Run by
Pfizer
See details and how to joinNCT07772921 · EU 2026-526565-18-00
No phaseTaking people
NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)
Where
Research Triangle Park
Age
18 years to 60 years
People
400
Run by
National Institute of Environmental Health Sciences (NIEHS)
See details and how to joinNCT02327897
Phase 3Taking people
Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment
Where
Ann Arbor, Aurora, Bethesda, Cleveland, Durham, Northfield, Salt Lake City, The Bronx
Age
6 years and over
People
230 worldwide
Run by
AstraZeneca
See details and how to joinNCT07444567
No phaseTaking people
Study of the Effect of Innate on the Inflammatory Response to Endotoxin
Where
Research Triangle Park
Age
18 years to 100 years
People
725
Run by
National Institute of Environmental Health Sciences (NIEHS)
See details and how to joinNCT01143480
No phaseNot yet taking people in United States
R34 Asthma Depression
Where
New York
Age
60 years and over
People
60
Run by
Icahn School of Medicine at Mount Sinai
See details and how to joinNCT07895576
No phaseTaking people
BREATHE: An Efficacy-implementation Trial Among Black Adults With Uncontrolled Asthma
Where
Beacon, Brooklyn
Age
18 years and over
People
400
Run by
Columbia University
See details and how to joinNCT05341726