Sign in
TerminatedNo phase

The Longitudinal Study of Stimulant Use Disorder

Key facts

Who runs it
University of Texas Southwestern Medical Center
Where
Dallas, United StatesSee the site
Trial code
Status
Terminated
People taking part
72 people enrolled
Started
16 Nov 2023
Ended
31 Mar 2025
Type of study
Observational
Record updated
8 April 2025
Why it stopped
Funding

Who can take part

Age
18 years to 85 years
Sex
Women and men
Healthy volunteers
Can take part

The registry criteria, word for word

Show all 8 criteriaShow less

Who can take part

  • Be an adult between the ages of 18-85, inclusive
  • Be able to sufficiently understand, speak, and read English to provide informed consent and ask relevant questions
  • For participants with current/history of Stimulant Use Disorder: Subjects must meet MINI International Neuropsychiatric Inventory (MINI) criteria for current stimulant use disorder or meet MINI supplemental criterial for lifetime stimulant use disorder. For Healthy control individuals: Subjects must meet criteria for a healthy control: No history of substance use disorder or other mental illness as defined by the MINI International Neuropsychiatric Inventory (MINI)
  • Be willing to provide consent and comply with all procedure instructions
  • Be willing to provide blood samples and participate in EEGs and MRIs

Who cannot take part

  • For participants with stimulus use disorder cohort: Have a history of schizophrenia, schizoaffective disorders, or chronic psychotic disorders based on the MINI. For healthy control individuals: Have a history of substance use disorder or any other psychiatric disorder as defined by the MINI and supplemental questions
  • Have any condition for which study participation would not be in their best interest (e.g., cognitive impairment, unstable general medical condition, intoxication, active psychosis) or that could prevent, limit, or confound the protocol-specified assessments, in the opinion of the investigator or their designee
  • Require immediate hospitalization for psychiatric disorder or suicidal risk as assessed by a licensed study clinician

Where in United States

  • UT Southwestern Medical CenterDallas, United States

About the trial

What the trial wants to find out

This research is a 5-year observational, longitudinal registry study with no treatment or medication provided as part of participation. Individuals with current or lifetime stimulant use disorder, in addition to healthy control individuals, may be eligible to participate in this study. A variety of assessments and tasks including Magnetic Resonance Imaging (MRI), Electroencephalography (EEG), blood draws, urine drug screens, and both self-report and clinician-rated assessments will be used to assess biomarkers in this population. This study has a visit schedule of four in-person visits and eight remote visits per year.

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Observational Longitudinal Study of Individuals With Stimulant Use Disorder: Research and Development of a Biosignature
Record updated
8 April 2025