Tests yoga as a treatment for mild to moderate depression
Compares a 12-week yoga program with education in adults with depression.
Plain-language title generated from the registry record
Registry title: Treating Major Depression With Yoga Mono-therapy
Key facts
- Where
- San Francisco, United StatesSee the site
Where in United States
- Zuckerberg San Francisco General HospitalSan Francisco, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of California, San Francisco
- Trial code
- NCT06091527
- Record updated
- 6 November 2025
- Original description
The goal of this single-center, single-blind, randomized, controlled, parallel group, interventional trial is to evaluate antidepressant efficacy of yoga monotherapy of 12-weeks duration in 180 adults meeting diagnostic criteria for mild-to-moderate major depression at the Zuckerberg San Francisco General Hospital. Researchers will compare the yoga interventions to an education control intervention on holistic healthcare.Read full original descriptionShow less
Treating Major Depression With Yoga Mono-therapy: 12-Week Randomized Controlled Trial
The goal of this single-center, single-blind, randomized, controlled, parallel group, interventional trial is to evaluate antidepressant efficacy of yoga monotherapy of 12-weeks duration in 180 adults meeting diagnostic criteria for mild-to-moderate major depression at the Zuckerberg San Francisco General Hospital. Researchers will compare the yoga interventions to an education control intervention on holistic healthcare.
Inclusion: 18 years of age or older; Able to give voluntary, informed consent; English-speaking; Diagnosis of clinical depression.
Exclusion: Current use of antidepressant medication; Current engagement in psychotherapy; Current pregnancy; Significant medical issues interfering with yoga practice.