Tests supervised exercise rehabilitation for people with cardiac amyloidosis
Tests supervised cardiac rehabilitation exercise in adults with cardiac amyloidosis.
Plain-language title generated from the registry record
Registry title: CAPACITY (Cardiac Amyloidosis and Physical ACtivITY) Study
Key facts
- Where
- Charlotte, United StatesSee the site
Where in United States
- Sanger Heart and Vascular InstituteCharlotte, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Wake Forest University Health Sciences
- Trial code
- NCT06096675
- Record updated
- 21 July 2026
- Original description
Exercise training in patients with heart failure and preserved ejection fraction (HFpEF) has been associated with an improvement in cardiorespiratory fitness and quality of life.Read full original descriptionShow less
Pilot Study Evaluating Supervised Cardiac Rehabilitation in Patients With Cardiac Amyloidosis
Exercise training in patients with heart failure and preserved ejection fraction (HFpEF) has been associated with an improvement in cardiorespiratory fitness and quality of life.
Inclusion: Age > 18; New York Heart Association (NYHA) Class I-III Heart Failure; Able to Exercise; On stable treatment for their cardiac amyloidosis or under active surveillance; Life expectancy of at least 6 months; Ability to understand and the willingness to sign a written informed consent document in English, and the willingness/ability to comply with the protocol activities; Participant must be able and willing to follow the cardiac rehabilitation activities.
Exclusion: Gait instability or history of prior falls; NYHA Class IV Heart Failure; Pulmonary disease requiring home oxygen; In the opinion of the Principal Investigator, have a clinically significant comorbid disease that is likely to affect the ability of the patient to complete the trial, interfere with their ability with measurement of self-reported outcomes; Inability to provide informed consent; Inability to commit to in-person supervised exercise sessions for three one-hour sessions a week for 12 weeks.