Self-Management Program for Head and Neck Cancer Swelling and Tissue Hardening
Tests a self-care program for swelling and hardening in adults after head and neck cancer.
Plain-language title generated from the registry record
Registry title: Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]
Key facts
- Where
- Nashville and Philadelphia, United StatesSee the 2 sites
Where in United States
- Vanderbilt University Medical CenterNashville, United StatesTaking people
- University of PennsylvaniaPhiladelphia, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Abramson Cancer Center at Penn Medicine
- Trial code
- NCT06125743
- Record updated
- 10 November 2026
- Original description
The goal of this study is to evaluate the effectiveness of a standardized lymphedema and fibrosis self-management program (LEF-SMP) to improve LEF self-management and reduce LEF-associated symptom burden, functional deficits, and improve quality of life in head and neck cancer (HNC) survivors.Read full original descriptionShow less
Promoting Self-Management in Head and Neck Cancer Survivors With Lymphedema and Fibrosis [PROMISE Trial]
The goal of this study is to evaluate the effectiveness of a standardized lymphedema and fibrosis self-management program (LEF-SMP) to improve LEF self-management and reduce LEF-associated symptom burden, functional deficits, and improve quality of life in head and neck cancer (HNC) survivors.
Inclusion: >18 years of age; Post HNC primary treatment; No evidence of cancer (NED); Completion of initial lymphedema therapy for head and neck lymphedema; Unable to obtain lymphedema therapy due to barriers noted above; History of lymphedema on the face and neck, with or without fibrosis; Ability to understand English in order to complete questionnaires; Ability to perform self-care activities for LEF management; Ability to provide informed consent; Having an electronic device (a computer, tablet, iPad, or smartphone) and internet access at home; A valid email address.
Exclusion: Recurrent or metastatic cancer; Any other active cancer; Acute infection; Acute congestive heart failure; Acute renal failure; Cardiac or pulmonary edema; Uncontrolled hypertension; Venous thrombosis; Sensitive carotid sinus; Severe carotid blockage; Pregnant people; Incarcerated patients.