Home Exercise and Phone Coaching for Older Adults With Multiple Myeloma
Tests home exercise with remote monitoring and phone coaching in older adults with myeloma.
Plain-language title generated from the registry record
Registry title: Remote Monitoring With Health-Coaching to Improve Quality of Life in Older Patients With Multiple Myeloma
Key facts
- Where
- Rochester, United StatesSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 65 or older with multiple myeloma who are on maintenance treatment and have moderate or higher fatigue. It tests a home-based mindfulness activity program with remote monitoring and phone health coaching.
- Age
- 65 years or older
- Sex
- All sexes can join
- Disease stage
- Multiple myeloma, currently on maintenance treatment, with fatigue rated higher than 4 on a scale of 0-10 over the last week
- Earlier treatment
- At least 1 earlier line of treatment for multiple myeloma. Now on maintenance with a proteasome inhibitor and/or an immunomodulatory agent, and/or an anti-C38 antibody.
Main reasons for not taking part
- Cannot read and answer questions in English
- No wi-fi connection at home
- Fatigue rated 4 or lower on the 0-10 scale
Read by machine on 9 November 2026.
Where in United States
- Mayo Clinic in RochesterRochester, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Mayo Clinic
- Trial code
- NCT06145581
- Record updated
- 13 April 2026
- Original description
This clinical trial tests the effectiveness of a home-based mindfulness physical activity program with remote monitoring combined with structured telephone-based health coaching to decrease fatigue and improve quality of life in older patients with multiple myeloma (MM). Studies have shown that MM patients have the highest symptom burden among all blood cancers, with older patients experiencing more symptoms and problems, such as fatigue and decreased quality of life, compared to younger patients. There is some data to support that physical activity may have beneficial effects on fatigue, physical function, and quality of life in older cancer patients. Studies have also shown that older patients prefer activities that are gentle, holistic, and home-based. Mindfulness-based interventions have been shown to have positive effects on sleep, depression, anxiety and cancer-related fatigue. Health coaching is a patient centered behavioral change intervention that is delivered by various healthcare professionals and involves goal-setting, self-discovery, and accountability. Health coaching interventions have been shown to increase physical activity levels and improve quality of life. A home-based mindfulness physical activity program with remote monitoring combined with structured telephone-based health coaching may decrease fatigue and improve the quality of life in older patients with MM.Read full original descriptionShow less
Remote Monitoring With Health-Coaching for Lifestyle Changes in Older Patients With Multiple Myeloma
This clinical trial tests the effectiveness of a home-based mindfulness physical activity program with remote monitoring combined with structured telephone-based health coaching to decrease fatigue and improve quality of life in older patients with multiple myeloma (MM). Studies have shown that MM patients have the highest symptom burden among all blood cancers, with older patients experiencing more symptoms and problems, such as fatigue and decreased quality of life, compared to younger patients. There is some data to support that physical activity may have beneficial effects on fatigue, physical function, and quality of life in older cancer patients. Studies have also shown that older patients prefer activities that are gentle, holistic, and home-based. Mindfulness-based interventions have been shown to have positive effects on sleep, depression, anxiety and cancer-related fatigue. Health coaching is a patient centered behavioral change intervention that is delivered by various healthcare professionals and involves goal-setting, self-discovery, and accountability. Health coaching interventions have been shown to increase physical activity levels and improve quality of life. A home-based mindfulness physical activity program with remote monitoring combined with structured telephone-based health coaching may decrease fatigue and improve the quality of life in older patients with MM.
Inclusion: Diagnosed with MM and has received treatment with >= 1 prior lines of treatment, and currently on maintenance treatment with a proteasome inhibitor and/or immunomodulatory agent, and/or anti-C38 antibody; The ability to read and respond to questions in English; Age ≥ 65 years; Moderate or higher fatigue ( > 4) on a scale of 0-10 based on fatigue rating to question: - Rate your average fatigue over the last week, where 0 is no fatigue and 10 is extreme fatigue; Have wi-fi connection, as the program requires wi-fi to operate.
Exclusion: Does not meet listed inclusion criteria.