Studies hormone changes after a meal in people with cystic fibrosis
Looks at how hormones respond to a mixed meal in adults with cystic fibrosis.
Plain-language title generated from the registry record
Registry title: Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis
Key facts
- Where
- Cincinnati, United StatesSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 45 with cystic fibrosis who take highly effective CFTR modulator therapy. It studies hormone changes after a mixed meal.
- Age
- 18 to 45 years
- Sex
- Men and women can join.
- Disease stage
- Diagnosed with cystic fibrosis. People with and without cystic fibrosis related diabetes are mentioned in the record.
- Earlier treatment
- Must be receiving highly effective CFTR modulator therapy. Must not be using systemic glucocorticoids.
Main reasons for not taking part
- Transplant recipient
- Lung function drop or flare-up within the last 3 months
- Use of systemic glucocorticoids
- Pregnancy
- Any prior diabetic ketoacidosis
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Source: NCT06163482, who can take part
Where in United States
- University of CincinnatiCincinnati, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Cincinnati
- Trial code
- NCT06163482
- Record updated
- 25 August 2026
- Original description
In this exploratory study, the hormonal responses to a mixed meal will be examined in people with cystic fibrosis. The aim of this study is to find correlates with impaired glucose tolerance that is associated with this population.Read full original descriptionShow less
Changes in Postprandial Hormone Levels in Cystic Fibrosis Related Diabetes.
In this exploratory study, the hormonal responses to a mixed meal will be examined in people with cystic fibrosis. The aim of this study is to find correlates with impaired glucose tolerance that is associated with this population.
Inclusion: Diagnosed with cystic fibrosis; Aged 18 to 45 years; Males and females of any race and ethnicity; Receiving highly effective CFTR modular therapy.
Exclusion: Transplant recipient; Any prior history of diabetic ketoacidosis; Known liver disease that would be expected to significantly impact metabolic variable as interpreted by a study doctor; The presence of any other disease or condition, as interpreted by any one of the study doctors, that would be expected to confound the responses to liquid mixed meal or make participation in the study dangerous to the individual; Acute lung function decline or exacerbation within the last 3 months; Use of systemic glucocorticoids; Pregnancy; People who are cognitively impaired; People who do not speak English; For CFRD patients, a daily insulin requirement that exceeds 0.8 U/kg/day.