Cystic fibrosis trials in United States

In United States 83 Also abroad 188

83 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis
Where
Boston, Chapel Hill, Chicago, Denver, Falls Church, Hollywood, Long Beach, Los Angeles, Minneapolis, New York, Philadelphia, Salt Lake City, San Francisco, Santa Monica, Seattle
Age
18 years and over
People
64 worldwide
Run by
SpliSense Ltd.
See details and how to joinNCT06429176
Phase 3Taking people
Sinonasal Therapies and Histologic Correlations of Patients With Cystic Fibrosis in the Era of Highly Effective Modulator Therapy
Where
Indianapolis
Age
18 years and over
People
64
Run by
Indiana University
See details and how to joinNCT06996951
No phaseTaking people
Role of Genetic Factors in the Development of Lung Disease
Where
Bethesda
Age
2 years to 90 years
People
3,500
Run by
National Heart, Lung, and Blood Institute (NHLBI)
See details and how to joinNCT00001532
No phaseTaking people
Natural History of Bronchiectasis
Where
Bethesda
Age
5 years to 100 years
People
900
Run by
National Heart, Lung, and Blood Institute (NHLBI)
See details and how to joinNCT00943514
No phaseTaking people
Natural History of Noncirrhotic Portal Hypertension
Where
Bethesda
Age
12 years to 100 years
People
400
Run by
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
See details and how to joinNCT02417740
No phaseTaking people
Streamlined Treatment of Pulmonary Exacerbations in Pediatrics
Where
Ann Arbor, Atlanta, Aurora, Baltimore, Birmingham, Boston, Burlington, Chapel Hill, Charleston, Chicago, Cincinnati, Dallas, Houston, Indianapolis, Iowa City, Kansas City, Los Angeles, Madison, Milwaukee, Minneapolis, Palo Alto, Philadelphia, Pittsburgh, Portland, Richmond, Rochester, San Diego, Seattle, St Louis, Tucson
Age
3 years to 18 years
People
430 worldwide
Run by
University of Washington, the Collaborative Health Studies Coordinating Center
See details and how to joinNCT06654752
Phase 2Taking people
A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Adult Study Participants With Non-Cystic Fibrosis Bronchiectasis
Where
Brandon, DuBois, McKinney, Mesquite, Newport Beach, Plantation, Rock Hill
Age
18 years to 80 years
People
300 worldwide
Run by
UCB Biopharma SRL
See details and how to joinNCT07720375 · EU 2026-525524-18-00
No phaseEnrolling by invitation
Prospective Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria
Where
Austin, Baltimore, Charlottesville, Colchester, Dallas, Denver, Seattle
Age
1 month to 99 years
People
100
Run by
University of North Carolina, Chapel Hill
See details and how to joinNCT05686837
No phaseTaking people
TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age
Where
Aurora, Bloomington, Boston, Buffalo, Chapel Hill, Cincinnati, Hollywood, Orange, Orlando, Plano, Providence, Richmond, Seattle
Age
18 months to 11 years
People
600
Run by
State University of New York at Buffalo
See details and how to joinNCT07048574
Phase 2Taking people
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Where
Akron, Ann Arbor, Atlanta, Boston, Cleveland, Columbus, Dallas, Denver, Detroit, Gainesville, Glenview, Hershey, Iowa City, Kansas City, Lexington, Long Beach, Los Angeles, Madison, Milwaukee, Minneapolis, New Brunswick, Orlando, Pittsburgh, Portland, Salt Lake City, Toledo, Valhalla
Age
12 years and over
People
113
Run by
Anagram Therapeutics, Inc.
See details and how to joinNCT07450547 · EU 2025-524569-25-00
Phase 4Not yet taking people in United States
Iron Repletion in Cystic Fibrosis
Where
Ann Arbor, Charleston, Denver, Indianapolis, Kansas City, Minneapolis, New York, Omaha
Age
18 years and over
People
100
Run by
University of Michigan
See details and how to joinNCT07903311
Phase 2Taking people
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
Where
Ann Arbor, Atlanta, Augusta, Birmingham, Boston, Chapel Hill, Charleston, Columbus, Denver, Franklin, Hammond, Houston, Iowa City, Kansas City, Los Angeles, Miami, New York, Philadelphia, Portland, Rochester, Sacramento, Spartanburg, St Louis, Tyler, Union, Washington D.C., Williamsburg, Wilmington, Winston-Salem
Age
18 years to 80 years
People
284 worldwide
Run by
Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
See details and how to joinNCT06559150 · EU 2024-514845-12-00
No phaseNot yet taking people in United States
Novel Point-of-care Sweat Chloride Testing Device for Monitoring CFTR Function
Where
Atlanta
Age
2 weeks to 90 years
People
300
Run by
Emory University
See details and how to joinNCT07414810
Phase 1Taking people
Evaluation of VX-581 in Healthy Participants and in Participants With Cystic Fibrosis
Where
Overland Park
Age
18 years to 55 years
People
152
Run by
Vertex Pharmaceuticals Incorporated
See details and how to joinNCT07283770
Phase 1Taking people
Bacteriophages for Adults With Cystic Fibrosis and Chronic Achromobacter Lung Infection
Where
Pittsburgh
Age
18 years and over
People
12
Run by
Ghady Haidar
See details and how to joinNCT07275905
No phaseTaking people
Regional Phenotyping of CF and Non-CF Bronchiectasis
Where
Cincinnati
Age
5 years to 100 years
People
100
Run by
Children's Hospital Medical Center, Cincinnati
See details and how to joinNCT04793867
No phaseTaking people
Health Outcomes of Parents With Cystic Fibrosis-Aim 2
Where
Ann Arbor, Baltimore, Birmingham, Boston, Chapel Hill, Charleston, Dallas, Denver, Evanston, Indianapolis, Kansas City, Minneapolis, Philadelphia, Pittsburgh, Portland, Seattle, St Louis
Age
18 years and over
People
146
Run by
University of Pittsburgh
See details and how to joinNCT06296394
No phaseTaking people
Acoustic Waveform Respiratory Evaluation
Where
Indianapolis, Pittsburgh
Age
8 years to 70 years
People
800
Run by
Indiana University
See details and how to joinNCT06512064
No phaseTaking people
Exercise in Child Health
Where
Irvine
Age
10 years to 17 years
People
240
Run by
University of California, Irvine
See details and how to joinNCT05359991
Phase 2Taking people
A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.
Where
Baltimore, Billings, Cleveland, Columbus, Doral, Hershey, Lenexa, Little Rock, Los Angeles, Nashville, Oklahoma City, Orlando, Scottsdale
Age
18 years to 85 years
People
66 worldwide
Run by
Aimmune Nestlé Health Science US R&D, LLC
See details and how to joinNCT07559175
No phaseTaking people
ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Where
Baltimore
Age
8 years to 21 years
People
500
Run by
Johns Hopkins University
See details and how to joinNCT05463289
No phaseNot yet taking people in United States
Nutrition Supplement for Cystic Fibrosis
Where
Columbus
Age
18 years to 50 years
People
60
Run by
Ohio State University
See details and how to joinNCT07163078
No phaseEnrolling by invitation
Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs
Where
Baltimore, Boston, Charlottesville, Dallas, Durham, Houston, Jacksonville, Philadelphia, Phoenix, Pittsburgh, San Francisco, Stanford, The Bronx
People
3,500 worldwide
Run by
Paragonix Technologies
See details and how to joinNCT04930289
No phaseTaking people
Genetics of Insulin and Incretins in Cystic Fibrosis
Where
Philadelphia
Age
2 years and over
People
550
Run by
Children's Hospital of Philadelphia
See details and how to joinNCT01852448
No phaseTaking people
Impact of Sinus Surgery on Individuals With Cystic Fibrosis
Where
Aurora, Chapel Hill, Charleston, Denver, Los Angeles, Nashville, Portland, Salt Lake City, Stanford
Age
18 years to 99 years
People
170
Run by
University of California, Los Angeles
See details and how to joinNCT04469439