Physical Therapy vs Remote Exercise for Knee Pain Due to Osteoarthritis (OA)
Key facts
- Who runs it
- Icahn School of Medicine at Mount Sinai
- Where
- New York, United StatesSee the site
- Trial code
- Status
- Terminated
- People taking part
- 32 people enrolled
- Started
- 29 Jan 2024
- Ended
- 12 Feb 2025
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Technology-implemented exercise therapy
- Traditional Physical Therapy
- Record updated
- 6 February 2026
- Why it stopped
- Sponsor halted funding
Who can take part
- Age
- 18 years and older
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 14 criteriaShow less
Who can take part
- Adults (age ≥ 18 years)
- Living in the tristate area - CT/NY/NJ
- Symptomatic OA (National Institute for Health and Care Excellence clinical criteria for OA)
- Chronic knee pain (>3 months) as a primary pain complaint
- Average pain score ≥ 4 on an 11-point numeric rating scale at baseline
- Access to a device with internet connection
- KL Stages 1-2-3
Who cannot take part
- Prior documented history of cognitive impairment
- History of total knee arthroplasty
- History of: Inflammatory arthritis (e.g. rheumatoid arthritis); or any neuropathies affecting the lower limbs, spinal cord injury, spine fractures, advanced heart disease, bleeding issues (i.e. hemophilia), surgery within the last 90 days; fall within 90 days; high risk of fracture
- History of knee injury, within the last 3 months
- Present unstable/uncontrolled cardiovascular condition
- Undergoing active chemotherapy for cancer
- Currently engaged with other PT or strengthening program
Where in United States
- Abilities Research CenterNew York, United StatesNo longer taking part
About the trial
What the trial wants to find out
The purpose of this clinical study is to demonstrate that after six weeks of at home exercise, 3 times per week with SimpleTherapy, participants with clinical indications of knee OA will on average have improved outcomes noninferior than traditionally prescribed physical therapy regimens.
The 2 groups in the trial
- Technology-implemented exercise therapyTreatment being tested
Therapy plans performed at home overseen by a remote physical therapist via SimpleTherapy. Allocation to this group will require using smart devices or a computer/laptop to receive care. Remote visits with a PT typically last 45min long and home exercises suggested by the app are self-paced.
- Traditional Physical TherapyExisting treatment, for comparison
Participants will be prescribed an exercise plan by a physical therapist as normally would occur as part of standards of care outside the context of a research study. In-person assessments and at-home exercise suggestions will be decided by the physical therapist. Duration of PT appointments is typically 45 minutes long two times per week and are supplemented by PT recommended self-paced at-home exercises.
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Digital Home Exercise Program Versus Standard of Care for Chronic OA-related Knee Pain: a Non-inferiority Randomized Controlled Trial
- Record updated
- 6 February 2026