Tests extra sleep and its effect on blood fats in adults with overweight
Tests sleep extension in adults who sleep under 6.5 hours a night.
Plain-language title generated from the registry record
Registry title: Effect of Sleep Extension on Ceramides in People With Overweight and Obesity
Key facts
- Where
- Salt Lake City, United StatesSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18-45 with overweight or obesity who usually sleep less than 6.5 hours a night. It tests whether sleeping longer changes blood ceramides and insulin sensitivity.
- Age
- 18-45 years old
- Sex
- Men and women, in equal numbers
- Disease stage
- Body mass index (BMI) of 27.5-34.9 kg/m2. Usual total sleep time under 6.5 hours per night for the past 6 months, as reported by the person.
- Earlier treatment
- Cannot be in a weight loss or physical activity program such as the Diabetes Prevention Program. Cannot use prescription drugs or substances known to affect sleep or glucose metabolism, or blood thinners (anticoagulants).
- Biomarker or test result
- Fasting plasma glucose must be below 126 mg/dL (7 mmol/L) and HbA1c below 6.5% (48 mmol/mol).
Main reasons for not taking part
- Diagnosed sleep disorder or major psychiatric illness
- Significant organ disease, such as heart or kidney disease
- Diagnosed diabetes, or fasting plasma glucose 126 mg/dL (7 mmol/L) or higher, or HbA1c 6.5% (48 mmol/mol) or higher
- Pregnant or nursing, going through menopause or after menopause
- Shift work now or within the last year, or currently smoking
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Source: NCT06180837, who can take part
Where in United States
- College of Health Research Complex--University of UtahSalt Lake City, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Utah
- Trial code
- NCT06180837
- Record updated
- 5 August 2026
- Original description
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity. Participants will undergo a randomized controlled trial, with sleep extension (intervention) and healthy lifestyle (control) groups. The sleep extension is designed to increase participant's time in bed by 2 hours per night. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).Read full original descriptionShow less
Biomarkers of Habitual Short Sleep and Related Cardiometabolic Risk
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity. Participants will undergo a randomized controlled trial, with sleep extension (intervention) and healthy lifestyle (control) groups. The sleep extension is designed to increase participant's time in bed by 2 hours per night. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).
Inclusion: Age: 18-45 years old; equal numbers of men and women; Body mass index (BMI): 27.5-34.9 kg/m2; Sleep Habits: habitual self-reported average total sleep time (TST) <6.5 hours per night for prior 6 months.
Exclusion: Weight change: >10% of body weight over prior six months; Clinically diagnosed sleep disorder or major psychiatric illness; Evidence of significant organ dysfunction or disease (e.g., heart disease, kidney disease); Cancer that has been in remission less than 5 years; Shift-work: current or history of within last year; Current enrollment in weight loss or physical activity program like the Diabetes Prevention Program; Clinically diagnosed diabetes or fasting plasma glucose ≥126 mg/dL or HbA1c ≥6.5%; Use of prescription drugs or substances known to influence sleep or glucose metabolism, or anticoagulant medications; Pregnant/nursing, experiencing menopause or post-menopausal; Currently smoking; Alcohol intake>14 drinks per week or >3 drinks per day.