Exercise and Mediterranean Diet for Obesity and Fatty Liver Disease
Tests two exercise programs with a Mediterranean diet in adults with obesity and fatty liver.
Plain-language title generated from the registry record
Registry title: Effects of Two Different Exercise Programs and Diet in Obese Subjects With NAFLD
Key facts
- Where
- Castellana Grotte, ItalySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT06186869, who can take part
Where in Italy
- IRCCS De BellisCastellana Grotte, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
- Trial code
- NCT06186869
- Record updated
- 27 March 2026
- Original description
The aim of the study is to estimate the effectiveness of two different exercise programs combined with the Mediterranean diet versus diet alone on inflammatory status in subjects aged 18-65 years with obesity (BMI>30) and Non-Alcoholic Fatty Liver Disease (NAFLD) (CAP >248 dB/m).Read full original descriptionShow less
Effects of Two Different Exercise Programs Combined With the Mediterranean Diet on Inflammatory Status in Subjects With Obesity and NAFLD
The aim of the study is to estimate the effectiveness of two different exercise programs combined with the Mediterranean diet versus diet alone on inflammatory status in subjects aged 18-65 years with obesity (BMI>30) and Non-Alcoholic Fatty Liver Disease (NAFLD) (CAP >248 dB/m).
Inclusion: BMI ≥ 30 kg/m2 or an abdominal circumference (waist) > 94 cm in men and > 80 cm in women (IDF criteria for the definition of abdominal obesity) with or without the characteristics that characterise metabolic syndrome; Age range 18-65 years, both sexes; Diagnosis of hepatic steatosis, formulated on the basis of recognised criteria (fibroscan (CAP (controlled attenuation parameter) > 238 dB/m)).
Exclusion: Presence of any pathology that may influence the presence of steatosis apart from pathologies that are inclusion criteria, neurological and psychiatric pathologies, gastrointestinal, oncological and cardiovascular diseases; Normal and underweight subjects; Pregnancy or breastfeeding; Subjects with osteoarticular pathologies that may prevent regular exercise; Inability to quantify the degree of NAFLD by Fibroscan; Person not in possession of a medical certificate of fitness for non-competitive physical activity.