Obesity trials in Italy

In Italy 104 Also abroad 1939

104 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Precision Nutrition to Improve Cardiometabolic Health With Dietary (Poly)Phenols
Where
Parma
Age
40 years to 80 years
People
330
Run by
University of Parma
See details and how to joinNCT06347094
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Where
Bari, Bergamo, Bologna, Catanzaro, Palermo, Perugia, Pisa, Rome, San Donato Milanese
Age
18 years and over
People
2,000 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351045 · EU 2025-523104-71-00
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Where
Bari, Bergamo, Bologna, Catanzaro, Milan, Palermo, Perugia, Rome
Age
18 years and over
People
1,600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351058 · EU 2025-523106-32-00
No phaseTaking people
Effects of Obesity on Physical Abilities and Daily Living Activities in Elderly Adults
Where
Oggebbio
Age
65 years and over
People
160
Run by
Istituto Auxologico Italiano
See details and how to joinNCT07614464
No phaseTaking people
Bariatric Surgery and Gut Microbiota Changes Over Time
Where
Castellana Grotte
Age
18 years to 65 years
People
100
Run by
Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
See details and how to joinNCT07381140
Phase 3Taking people
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Where
Bologna, Chieti Scalo, Palermo, Rome, Sesto San Giovanni
Age
18 years and over
People
954 worldwide
Run by
Pfizer
See details and how to joinNCT07595549 · EU 2026-525318-75-00
Phase 3Taking people
A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity
Where
Florence, Milan, Palermo, Pisa
Age
18 years and over
People
3,900 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07843498 · EU 2026-526188-39-00
Phase 3Not yet taking people in Italy
A Research Study to Investigate How Well the Medicine CagriSema Lowers High Blood Pressure in People Living With High Blood Pressure and Obesity
Where
Ancorna, Bari, Brescia, Catanzaro, Ferrara, Milan, Padova, Palermo, Pozzilli (IS), Rome, Siena
Age
18 years and over
People
1,408 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07919405
Phase 3Taking people
A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)
Where
Florence, Modena, Novara, Parma, Roma, Verona
Age
6 years to 17 years
People
125 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06672549
Phase 3Taking people
A Study of Orforglipron (LY3502970) in Adolescent Participants With Obesity, or Overweight With Related Comorbidities
Where
Florence, Novara, Rome, Verona
Age
12 years to 17 years
People
150 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06672939 · EU 2024-514081-40-00
Phase 3Taking people
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Where
Bologna, Castellana Grotte, Milan, Padova, Pisa, Rho, Roma, Rozzano
Age
18 years to 70 years
People
350 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06937086 · EU 2024-520209-38-00
Phase 3Taking people
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Where
Bologna, Castellana Grotte, Milan, Padova, Pisa, Rho, Roma, Rozzano
Age
18 years to 70 years
People
290 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06937099 · EU 2024-520210-21-00
Phase 3Taking people
Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)
Where
Florence, Modena, Novara, Parma, Roma
Age
6 years to 11 years
People
150 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07817875 · EU 2025-522020-27-00
Phase 3Not yet taking people in Italy
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk
Where
Arezzo, Bologna, Chieti Scalo, Florence, Milan, Modena, Naples, Padova, Parma, Pisa, Rome, Rozzano, Siena, A.O.U. Policlinico Paolo Giaccone, Osepdale Civile Fr 5, ASL Città di Torino
Age
45 years to 64 years
People
3,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07900633 · EU 2026-525919-14-00
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Where
Bologna, Milan, Palermo, Pisa, Rome, Rozzano, Sesto San Giovanni, Turin
Age
18 years and over
People
2,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784725 · EU 2025-523379-41-00
No phaseTaking people
Investigating the Link Between Advanced Glycation End Products (AGEs) and Muscle Wasting in Sarcobesity
Where
Novara
Age
18 years and over
People
195
Run by
Azienda Ospedaliero Universitaria Maggiore della Carita
See details and how to joinNCT06438900
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Where
Bari, Bergamo, Brescia, Cortona AR, Foggia, Forlì, Milan, Naples, Parma, Pavia, Rimini, Rivoli, Roma, Sassari
Age
18 years to 99 years
People
5,056 worldwide
Run by
Amgen
See details and how to joinNCT07037459
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity (MARITIME-HF)
Where
Bari, Bergamo, Brescia, Cortona, Foggia, Forli', Milan, Naples, Parma, Pavia, Rimini, Rivoli, Rome, Rozzano, Sassari
Age
18 years and over
People
2,787 worldwide
Run by
Amgen Inc.
See details and how to join2024-516654-22-00 · EU 2024-516654-22-00
No phaseTaking people
Clinical Study on Circadian Genes Dysregulation in Patients With Glucocorticoid Disorders
Where
Roma
Age
18 years to 80 years
People
44
Run by
University of Roma La Sapienza
See details and how to joinNCT04374721
No phaseTaking people
MORPH-A - Multidisciplinary Obesity Rehabilitation & Psychophysical Health and Awareness
Where
Pavia
Age
18 years and over
People
34
Run by
Istituti Clinici Scientifici Maugeri SpA
See details and how to joinNCT07880847
Phase 3Taking people
A Master Protocol to Investigate Efficacy and Safety of Elecoglipron in Participants With Obesity or Overweight With or Without T2DM
Where
Bologna, Catania, Chieti, Florence, Latina, Milan, Pisa, Ravenna, Roma, San Donato
Age
18 years and over
People
4,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07667803
No phaseNot yet taking people in Italy
ENDOBARIHEART STUDY
Where
Cotignola
Age
18 years and over
People
50
Run by
Maria Cecilia Hospital
See details and how to joinNCT07847307
Phase 3Not yet taking people in Italy
A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity
Where
Acquaviva delle Fonti, Bari, Bergamo, Castellana Grotte, Catanzaro, Chieti Scalo, Cosenza, Ferrara, Florence, Grosseto, Latina, Lucca, Milan, Naples, Negrar, Orbassano, Padova, Rimini, Rome, Salerno, Sesto San Giovanni, Siena, Turin, Venice
Age
45 years to 64 years
People
8,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07861100 · EU 2026-525182-53-00
No phaseTaking people
Comparing the Efficacy and Safety of the EndoZip System and Apollo ESG in Obese Patients
Where
Roma
Age
21 years to 65 years
People
184 worldwide
Run by
Nitinotes Surgical Ltd.
See details and how to joinNCT07090005
Phase 3Taking people
A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight
Where
Milan, Novara, Trieste, Verona
Age
8 years to 18 years
People
460 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07253285 · EU 2023-509176-42-00