Nifedipine to Lower Blood Pressure After Preeclampsia Pregnancy
Tests nifedipine to control blood pressure in women after preeclampsia pregnancy.
Plain-language title generated from the registry record
Registry title: Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia
Key facts
- Where
- Chicago and Milwaukee, United StatesSee the 2 sites
Where in United States
- Northwestern UniversityChicago, United StatesTaking people
- Medical College of WisconsinMilwaukee, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Medical College of Wisconsin
- Trial code
- NCT06220721
- Record updated
- 20 July 2026
- Original description
The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.Read full original descriptionShow less
Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia
The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.
Inclusion: Hypertensive disorders of pregnancy (HDP) diagnosis, specifically gestational hypertension, preeclampsia, eclampsia, or HELLP syndrome, according to ACOG guidelines; Postpartum day 0-4; Age ≥ 18 years; Able to communicate in English or in Spanish; Has an established OBGYN at an MCW or NU health system practice that has access to Epic electronic medical records.
Exclusion: Already taking long-acting antihypertensive medication for standard care; Pre-gestational hypertension; Type 1 or type 2 diabetes mellitus; Known allergy or contraindication to nifedipine ER; Maternal conditions that impact study outcomes: sickle cell disease, systemic lupus erythematosus; Admitted to intensive care unit at the time of screening; Diagnosed with HDP during postpartum readmission after discharge from delivery hospitalization; Getting discharged on the day of screening; Inability or unwillingness to provide informed consent.