Smartphone App Tested for Psychological Wellbeing in Crohn's Disease
Tests a smartphone app for stress and wellbeing in adults with Crohn's disease.
Key facts
- Who runs it
- Soroka University Medical Center
- Where
- Beersheba, Haifa, Petah Tikva, and Ramat Gan, IsraelSee the 4 sites
- Trial code
- Registry title
- A Smartphone Application for Added Psychological Wellbeing in Crohn's Disease
- Status
- Recruiting
- People taking part
- 200 people, planned
- Started
- 1 Aug 2023
- Expected to end
- 1 Aug 2027
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- COBMINDEX digital application
- Human therapist (Control)
- Record updated
- 30 April 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for Hebrew-speaking adults with Crohn's disease on stable treatment who can use a smartphone app for psychological wellbeing.
- Age
- 18 to 75 years
- Sex
- Men and women can join.
- Disease stage
- Proven Crohn's disease, diagnosed at least 3 months ago. Any Harvey Bradshaw Index score.
- Earlier treatment
- Stable medical treatment for the last 3 months.
Main reasons for not taking part
- Ulcerative colitis or unclassified inflammatory bowel disease
- Planned surgery for Crohn's disease, or surgery in the last 3 months (except drainage of a perianal abscess)
- Psychiatric disease (schizophrenia, major depression or bipolar disorder)
- Alcohol or drug dependency (stable medical use of cannabinoids is allowed)
- Pregnancy or planned pregnancy during the study
The registry criteria, word for word
Show all 15 criteriaShow less
Who can take part
- Willingness to participate and signed informed consent
- Hebrew-speaking
- Age 18-75
- Proven diagnosis of Crohn's disease, at least 3 months post-diagnosis
- Stable medical treatment for the last 3 months
- Any Harvey Bradshaw Index score
- Ability to operate a smartphone and cellular application
Who cannot take part
- Alcohol or drug dependency (stable medical use of cannabinoids will be allowed)
- Diagnosis of ulcerative colitis or unclassified inflammatory bowel disease
- Planned surgery for Crohn's disease
- Surgery for Crohn's disease (excluding drainage of perianal abscess) in the last 3 months
- Psychiatric disease (schizophrenia, major depression or bipolar disorder)
- Pregnancy or planned pregnancy during study period
- Clinically significant comorbidity
- Former participation in COBMINDEX trials
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 75 years old?
Where in Israel
- Soroka University Medical CenterBeersheba, IsraelContact: Doron Schwartz, MDTaking people
- Rambam Health Care Campus iHaifa, IsraelContact: Haggai Bar-Yoseph, MDNot yet recruiting
- Belinson Medical CenterPetah Tikva, IsraelContact: Henat Yanai, MDNot yet recruiting
- Sheba medical centerRamat Gan, IsraelContact: Adi Lahat -Zok, Prof.Not yet recruiting
About the trial
What the trial wants to find out
Psychological intervention by COBMINDEX application to reduce psychological stress among CD patients, fatigue and pain and improve the patients' well being, quality-of-life and disease-coping skills, as well as improvement of the patients' immunological profile and intestinal microbiome.
The 2 groups in the trial
- Intervention- COBMINDEX applicationTreatment being tested
The intervention in this arm is to learn during the first 3 months, cognitive, behavioral and mindfulness based stress reduction with daily exercise using a research dedicated application. Than, additional 9 months of practicing daily only with the application.
Treatment: COBMINDEX digital application
- Control- COBMINDEX with Human therapistExisting treatment, for comparison
The intervention in this arm is to learn during the first 3 months, cognitive, behavioral and mindfulness based stress reduction with daily exercise with human therapist, and than practicing daily only with the application.
Treatment: Human therapist (Control)
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Israeli IBD Research Nucleus (IIRN) Consortium: COBMINDEX Goes Forward- A Smartphone Application for Added Psychological Wellbeing in Crohn's Disease
- Plain-language title
- Smartphone App Tested for Psychological Wellbeing in Crohn's DiseaseGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06221254, who can take part
- Record updated
- 30 April 2026