Tests diosmin for finger sores in people with systemic sclerosis
Tests diosmin against placebo for finger sores in adults with systemic sclerosis.
Plain-language title generated from the registry record
Registry title: Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis
Key facts
- Where
- Calgary, Halifax, London, Ottawa, and Toronto, CanadaSee the 5 sites
Where in Canada
- University Of CalgaryCalgary, CanadaTaking people
- Dalhousie UniversityHalifax, CanadaTaking people
- Saint Joseph Health Care CentreLondon, CanadaTaking people
- The Ottawa HospitalOttawa, CanadaTaking people
- Mount Sinai Health SystemToronto, CanadaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Primus Pharmaceuticals
- Trial code
- NCT06256575
- Record updated
- 10 November 2026
- Original description
This study is performed to consider the safety and healing ability of diosmin in patients with systemic sclerosis (scleroderma) and open sores on their fingers (digital ulcers). Two (2) out of three (3) participants will receive active product. The participants will have four (4) visits over eight (8) weeks. Physical exams and photos will be performed. A variety of questions will be asked describing level of pain and lifestyle changes.Read full original descriptionShow less
Treatment of Digital Ulcers in Systemic Sclerosis With Diosmin: A Randomized, Double-blind, Placebo-controlled Multi-centre Pilot Study
This study is performed to consider the safety and healing ability of diosmin in patients with systemic sclerosis (scleroderma) and open sores on their fingers (digital ulcers). Two (2) out of three (3) participants will receive active product. The participants will have four (4) visits over eight (8) weeks. Physical exams and photos will be performed. A variety of questions will be asked describing level of pain and lifestyle changes.
Inclusion: Diagnosis of systemic sclerosis (scleroderma); At least one "active" digital ulcer; Medication for systemic sclerosis unchanged for 30 days.
Exclusion: Infection or gangrene in ulcer; Citrus allergy; Unstable heart, kidney, or liver disease; Active infection of any type; Current cancer treatment or uncured cancer; Pregnancy or breast feeding.