Systemic sclerosis (scleroderma) trials in Canada

In Canada 13 Also abroad 213

13 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Study of Diosmin for the Treatment of Digital Ulcers in Systemic Sclerosis
Where
Calgary, Halifax, London, Ottawa, Toronto
Age
18 years and over
People
45
Run by
Primus Pharmaceuticals
See details and how to joinNCT06256575
Phase 3Taking people
Rollover Study for Participants Who Have Completed a Previous Clinical Study With Anifrolumab (Saphnelo) and Clinically Benefited From Continued Treatment
Where
Québec, Toronto
Age
5 years to 80 years
People
1,072 worldwide
Run by
AstraZeneca
See details and how to joinNCT07691970
Phase 1Taking people
A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease
Where
Montreal
Age
18 years to 74 years
People
66 worldwide
Run by
Allogene Therapeutics
See details and how to joinNCT07085104
Phase 2Not yet taking people in Canada
Mycophenolate After Stem Cell Transplant for Systemic Sclerosis
Where
Ottawa
Age
18 years and over
People
6
Run by
Ottawa Hospital Research Institute
See details and how to joinNCT07734012
Phase 3Taking people
A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis
Where
Calgary, Edmonton, London, Toronto
Age
18 years and over
People
448 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT07497087 · EU 2025-523884-39-00
Phase 1Taking people
Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
Where
Toronto
Age
18 years and over
People
300 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT03816345
Phase 2Taking people
Extracorporeal Photopheresis in Early Diffuse Cutaneous Systemic Sclerosis
Where
London
Age
18 years and over
People
15
Run by
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
See details and how to joinNCT04986605
Phase 2Taking people
Mycophenolate Mofetil in Systemic Sclerosis With Subclinical Interstitial Lung Disease
Where
Montreal, Québec
Age
18 years and over
People
35
Run by
Centre hospitalier de l'Université de Montréal (CHUM)
See details and how to joinNCT05785065
Phase 1Enrolling by invitation
A Study of KITE-363 in Participants With Refractory Autoimmune Diseases
Where
Montreal, Ottawa
Age
18 years and over
People
52 worldwide
Run by
Kite, A Gilead Company
See details and how to joinNCT07038447
Phase 3Not yet taking people in Canada
A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis
Where
Halifax, Sherbrooke
Age
16 years and over
People
92 worldwide
Run by
Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
See details and how to joinNCT07335562 · EU 2025-524337-11-00
No phaseTaking people
Skeletal Muscle Function in Interstitial Lung Disease
Where
Vancouver
Age
40 years to 80 years
People
40
Run by
University of British Columbia
See details and how to joinNCT03800017
No phaseEnrolling by invitation
Elastography Ultrasound in Localized Scleroderma (Morphea) Study
Where
Toronto
Age
Up to 18 years
People
20
Run by
The Hospital for Sick Children
See details and how to joinNCT06847750
Phase 1/2Taking people
Treatment With Human Umbilical Cord-derived Mesenchymal Stromal Cells in Systemic Sclerosis
Where
Montreal
Age
18 years and over
People
18
Run by
Marie Hudson, MD
See details and how to joinNCT04356287