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Differences between men and women in blood pressure control with obstructive sleep apnea

Looks at how men and women with untreated obstructive sleep apnea regulate blood pressure.

Key facts

Who runs it
Mayo Clinic
Where
Rochester, United StatesSee the site
Trial code
Registry title
A Study of Sex Differences in Neurocirculatory Control
Status
Recruiting
People taking part
60 people, planned
Started
29 Oct 2024
Expected to end
Mar 2027
Type of study
Observational
Record updated
7 January 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with obstructive sleep apnea (breathing stops during sleep) that has not been treated. It studies differences between men and women in blood pressure control.

Age
20 to 70 years
Sex
All sexes
Disease stage
Obstructive sleep apnea that has not been treated
Earlier treatment
No treatment for sleep apnea so far. No nicotine products in the 2 years before study visits.

Main reasons for not taking part

  • Heart disease such as coronary artery disease or heart failure
  • Pregnancy
  • COPD, diabetes or chronic kidney disease (CKD)
  • Sleep disorders other than OSA, shift work, usually going to sleep after midnight, or travel across ≥2 time zones within one week of study visits
  • BMI ≥40.0kg/m2, or use of allopurinol, proton pump inhibitors or other medicines or supplements that affect the study measurements

The registry criteria, word for word

Show all 14 criteriaShow less

Who can take part

  • 20-70 years of age

Who cannot take part

  • Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with outcome measures
  • Coronary artery disease
  • Heart failure
  • Diabetes
  • Sleep disorders other than OSA
  • Pregnancy
  • COPD
  • CKD
  • Shift workers
  • Individuals who typically go to sleep after midnight
  • Individuals who traveled across ≥2 time zones within one week of study visits
  • BMI ≥40.0kg/m2
  • Use of nicotine-containing products within the two years preceding study visits

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 20 and 70 years old?

Where in United States

  • Mayo Clinic in RochesterRochester, United StatesContact: Joshua Bock, PhDTaking people

About the trial

What the trial wants to find out

The purpose of this study is to investigate potential sex differences in neurocirculatory control of blood pressure in patients with untreated obstructive sleep apnea (OSA).

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Sex Differences in Neurocirculatory Control With Obstructive Sleep Apnea
Plain-language title
Differences between men and women in blood pressure control with obstructive sleep apneaGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 14 November 2026.
Fit questions
Built from NCT06261034, who can take part
Record updated
7 January 2026