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Studies how talking with others affects speech in people with ALS

Tests how structured conversation affects speech in adults with ALS.

Plain-language title generated from the registry record
Registry title: Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications

Key facts

Where
University Park, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 90 years old?

Source: NCT06266403, who can take part

Where in United States

  • Speech Core, Pennsylvania State UniversityUniversity Park, United StatesTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Penn State University
Trial code
NCT06266403
Record updated
7 August 2026
Original description
The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and age-matched speakers.Read full original descriptionShow less

Evaluating Verbal Communication in Structured Interactions: Theoretical and Clinical Implications

The goal of this clinical trial is to learn about the effect of communicative interaction on verbal communication in people with amyotrophic lateral sclerosis (ALS) and age-matched speakers.

The question is, What are the effects of communicative interaction on verbal communication in people with ALS?

Participants will read words and sentences while they are in a solo setting and interactive setting.

Inclusion: Speakers with amyotrophic lateral sclerosis (ALS) (PALS-people with ALS); diagnosis of ALS following the revised EL Escorial criteria; no history of other neurological conditions (e.g., stroke); no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA); detectable speech disturbance according to the ALS Functional Rating Scale-Revised (ALSFRS-R); the ability to produce single words; being a native speaker of American English (AE); Age-matched Speakers; passing the remote hearing screening; having no known speech, language, or neurological disorders per self-report; no cognitive impairment assessed by Telephone Montreal Cognitive Assessment (mini MoCA); being a functionally native monolingual speaker of American English; Unfamiliar Interlocutors; passing the remote hearing screening; having no known speech, language or neurological disorders per self-report; being a native monolingual speaker of American English; having no experience communicating with people with dysarthria; being between the ages of 18 and 40.

Exclusion: None - if volunteer meets the inclusion criteria, then they will be enrolled.

ClinicalTrials.gov NCT06266403