Studies how sleep problems relate to long-term effects after COVID-19
Observes whether sleep trouble and sleep apnea relate to lasting COVID-19 symptoms in adults.
Key facts
- Who runs it
- VA Office of Research and Development
- Where
- Detroit, United StatesSee the site
- Trial code
- Registry title
- Predictors of Post-COVID-19 Clinical and Cognitive Consequences
- Status
- Recruiting
- People taking part
- 200 people, planned
- Started
- 19 Jan 2023
- Expected to end
- 31 Dec 2026
- Type of study
- Observational, 2 groups
- Record updated
- 23 January 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who have had COVID-19, including people with sleep apnea (OSA) who have had COVID-19. It studies sleep, thinking, exercise ability and lung function after COVID-19.
- Age
- 18 years or older
- Sex
- All genders
- Disease stage
- Past COVID-19 infection. For people with obstructive sleep apnea (OSA): apnea hypopnea index of 5/hour on polysomnography.
Main reasons for not taking part
- Cannot give consent
- Active suicidal symptoms
- Children of all ages
- Pregnant women
The registry criteria, word for word
Show all 7 criteriaShow less
Who can take part
- All individuals 18 years or older, with prior history of COVID-19 infection diagnosis
- Both genders including all racial and ethnic groups
- Patients with OSA (apnea hypopnea index of 5/hour on polysomnography) with history of COVID-19 infection will be eligible with prior history of COVID-19 infection and without COVID-19 for Aim 2
Who cannot take part
- Children of all ages
- Inability to give consent
- Active suicidal symptoms
- Pregnant women
Where in United States
- John D. Dingell VA Medical Center, Detroit, MIDetroit, United StatesContact: Ruchi Rastogi, MSTaking people
About the trial
What the trial wants to find out
The CDC describes Post-acute sequelae of SARS-COV-2 infection (PASC) for the wide range of physical and mental health consequences experienced by some patients. These sequelae may be present four or more weeks after SARS-COV-2 infection, including patients who had initial mild or asymptomatic acute infection. However, there is complete absence of data whether chronic sleep changes due to COVID-19 infection may influence these physical and mental health consequences. While fatigue is one of the common post-COVID conditions, there are no systematic examinations of sleep disturbances in COVID-19 survivors. This will be a pilot observational retrospective and prospective cohort study, to systematically assess if sleep disturbances and severity of sleep apnea comprise a modifiable facet of PASC as well as the short-term and longer-term effects of COVID-19 infection itself on sleep, cognitive function, exercise capacity and lung function.
The 2 groups in the trial
- COVID+
Patients with post-acute sequelae of SARS-COV-2 infection (PSAC) and obstructive sleep apnea (OSA)
- Control
Patients with obstructive sleep apnea and no history of COVID-19
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Predictors of Post-COVID Clinical and Cognitive Consequences
- Plain-language title
- Studies how sleep problems relate to long-term effects after COVID-19Generated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Record updated
- 23 January 2026