Tests the ENDOPLY device for gastric plication in adults with obesity
Checks whether the ENDOPLY device is safe and workable in adults with obesity.
Plain-language title generated from the registry record
Registry title: ENDOPLY System in Humans: a Pilot Study
Key facts
- Where
- Brno, CzechiaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with class I or II obesity (BMI 30-40) who have tried several diets without success. It tests a stomach folding device called the ENDOPLY System.
- Age
- Above 18 and below 60 years
- Sex
- All sexes can join
- Disease stage
- Class I and II obesity, BMI 30-40
- Earlier treatment
- Must have failed multiple diet attempts. Cannot have had bariatric surgery or an endoscopic bariatric technique before.
Main reasons for not taking part
- Achalasia or other oesophageal motility disorders
- Severe esophagitis or gastroduodenal ulcer
- Untreated heart disease or hypertension
- Lung, kidney or liver failure, or cancer
- Pregnancy ongoing, scheduled or in the past months
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT06292728, who can take part
Where in Czechia
- Fakultní nemocnice u sv. Anny v Brně, Gastroenterologické a hepatologické odděleníBrno, CzechiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- ENDOPLY
- Trial code
- NCT06292728
- Record updated
- 10 September 2026
- Original description
Prospective, non-randomized study aimed at defining the initial pattern of gastric plication with the ENDOPLY System, and assess feasibility, ergonomics and safety of the device Prospective, single-centre, open label, consecutive enrolmentRead full original descriptionShow less
Safety and Feasibility of the ENDOPLY System in Humans: a Pilot Study
Prospective, non-randomized study aimed at defining the initial pattern of gastric plication with the ENDOPLY System, and assess feasibility, ergonomics and safety of the device Prospective, single-centre, open label, consecutive enrolment
Inclusion: BMI 30-40, i.e. class I and II obese patients; Age above 18 and below 60 years; Having failed multiples diet attempts.
Exclusion: Previous bariatric surgery or endoscopic bariatric technique; Achalasia and other oesophageal motility disorders; Gastroduodenal ulcer; Heart disease and hypertension without treatment; Pulmonary, renal or hepatic failure, cancer; Severe esophagitis; Pregnancy ongoing, scheduled or in the past months; Participation to another study.