Obesity trials in Czechia

In Czechia 36 Also abroad 1939

36 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Where
České Budějovice, Náchod, Plzeň 3, Prague, Prague 4, Praha 2
Age
18 years and over
People
2,000 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351045 · EU 2025-523104-71-00
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Where
Brandýs nad Labem, Jesenice, Prague, Prague 6, Praha, Praha 6
Age
18 years and over
People
1,600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351058 · EU 2025-523106-32-00
Phase 3Taking people
A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity
Where
Brno, České Budějovice, Habry, Moravska Ostrava A Privoz, Prague, Praha 9, Uherské Hradiště
Age
18 years and over
People
2,001 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07794579 · EU 2026-526175-35-00
Phase 3Taking people
A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes
Where
Brandýs nad Labem, Brno-Stred, Lazce, Náchod, Ostrava, Prague
Age
18 years and over
People
600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07843485 · EU 2026-526189-25-00
Phase 3Taking people
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Where
Brno, Hradec Králové, Ostrava, Prague, Ústí nad Labem
Age
18 years to 70 years
People
350 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06937086 · EU 2024-520209-38-00
Phase 3Taking people
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Where
Brno, Hradec Králové, Ostrava, Prague, Ústí nad Labem
Age
18 years to 70 years
People
290 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06937099 · EU 2024-520210-21-00
No phaseTaking people
National Childhood Obesity Prevention Programme BE FIT 24
Where
Prague
Age
6 years to 11 years
People
1,000
Run by
Institute of Health Information and Statistics of the Czech Republic
See details and how to joinNCT07057453
No phaseTaking people
Safety and Effectiveness of Orbera365™ Intragastric Balloon System
Where
Prague
Age
18 years and over
People
200 worldwide
Run by
Boston Scientific Corporation
See details and how to joinNCT07062094
Phase 3Taking people
A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight
Where
Benešov, Brno, Karlovy Vary, Náchod, Olomouc, Ostrava, Pilsen, Prague
Age
18 years and over
People
1,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07202884 · EU 2025-522514-23-00
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Where
Krnov, Ostrava, Prague 1, Praha 1
Age
18 years and over
People
1,035 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07282600 · EU 2025-523658-15-00
Phase 3Taking people
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
Where
Brno-Sever, Brno-Stred, Ostrava, Pardubice I, Uherské Hradiště
Age
18 years and over
People
900 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07353931 · EU 2025-523768-19-00
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Where
Holešov, Prague, Prague 8, Praha 4
Age
18 years and over
People
900 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07392190 · EU 2025-523659-73-00
Phase 3Not yet taking people in Czechia
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, Type 2 Diabetes, and Increased Cardiovascular Risk
Where
Náchod, Nový Jičín, Prague, Roudnice Nad Labem, Usti Nad Labem
Age
45 years to 64 years
People
3,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07900633 · EU 2026-525919-14-00
Phase 3Taking people
Maridebart Cafraglutide versus Placebo in Adult Participants with Obstructive Sleep Apnea not on Positive Airway Pressure Therapy (MARITIME-OSA-2)
Where
Benesov, Brno, Moravska Ostrava A Privoz
Age
18 years and over
People
120 worldwide
Run by
Amgen Inc.
See details and how to join2025-522699-94-00 · EU 2025-522699-94-00
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus
Where
Benešov, Brno-Stred, Hodonín, Kladno, Moravska Ostrava A Privoz, Prague, Prague 10, Prague 14, Sedlcany, Steti, Votice
Age
18 years and over
People
2,500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07784725 · EU 2025-523379-41-00
Phase 3Taking people
Efficacy and Safety of Once-Daily Oral ASC30 Compared with Placebo in Participants with Obesity or Overweight with Weight-Related Comorbidities
Where
Pardubice, Praha 2, Praha 5, Uherské Hradiště
Age
18 years and over
People
932 worldwide
Run by
Ascletis Pharma (China) Co. Ltd.
See details and how to join2026-526172-23-00 · EU 2026-526172-23-00
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
Where
Brandýs nad Labem, Brno, Broumov, Bruntál, Chlumec nad Cidlinou, Chomutov, Havirov - Mesto, Holešov, Hradec Králové, Jaroměř, Liberec, Mělník, Náchod, Olomouc, Ostrava, Pardubice, Prague, Praha 5 - Smichov, Přerov, Prostějov, Slaný, Trutnov, Uherské Hradiště, Ústí nad Labem
Age
18 years to 99 years
People
5,056 worldwide
Run by
Amgen
See details and how to joinNCT07037459
Phase 3Taking people
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity (MARITIME-HF)
Where
Brandýs nad Labem, Brno, Brno-Královo Pole, Brno-Stred, Brno-Zidenice, Broumov, Bruntal, Chlumec nad Cidlinou, Chomutov, Havířov, Holesov, Horni Brana, Horni Predmesti, Hradec Králové, Jaroměř, Liberec, Melnik, Moravska Ostrava A Privoz, Náchod, Olomouc, Ostrava, Pardubice, Pardubice I, Prague, Prague 1, Prague 2, Prerov I-Mesto, Prostějov, Slaný, Uherske Hradiste, Uherské Hradiště, Usti nad Labem, Ústí nad Labem, Valasske Mezirici
Age
18 years and over
People
2,787 worldwide
Run by
Amgen Inc.
See details and how to join2024-516654-22-00 · EU 2024-516654-22-00
Phase 3Taking people
Efficacy and Safety of Once-Daily Oral ASC30 Compared with Placebo in Participants with Obesity or Overweight with Type 2 Diabetes Mellitus
Where
Pardubice, Praha 2, Praha 5, Uherské Hradiště
Age
18 years and over
People
549 worldwide
Run by
Ascletis Pharma (China) Co. Ltd.
See details and how to join2026-526336-39-00 · EU 2026-526336-39-00
No phaseNot yet taking people in Czechia
Exercise Snacks Enabled by an mHealth Intervention Delivered in General Practice to Promote a Sustainable Active Lifestyle in Adults With Obesity
Where
Ostrava, Prague
Age
18 years to 65 years
People
306
Run by
Charles University, Czech Republic
See details and how to joinNCT07867665
Phase 3Not yet taking people in Czechia
A Research Study to Look at How Well Zenagamtide Works Compared to Placebo in People With Established Atherosclerotic Cardiovascular Disease and Either Overweight or Obesity
Where
Brandýs nad Labem, Brno, Broumov, České Budějovice, Chlumec Nad Cidlinou Iv, Chrudim IV, Hodonín, Horni Predmesti, Humpolec, Konska, Louny, Mariánské Lázně, Olomouc, Prague, Prague 13, Prague 2, Prague 8, Praha, Přerov, Prerov I-Mesto, Prostějov, Říčany, Slaný, Smiřice, Uherské Hradiště, Zlín
Age
45 years to 64 years
People
8,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07861100 · EU 2026-525182-53-00
Phase 3Taking people
Maridebart Cafraglutide versus Placebo in Adult Participants with Obstructive Sleep Apnea on Positive Airway Pressure Therapy (MARITIME-OSA-1)
Where
Benesov, Brno, Moravska Ostrava A Privoz
Age
18 years and over
People
115 worldwide
Run by
Amgen Inc.
See details and how to join2025-522703-14-00 · EU 2025-522703-14-00
Phase 3Taking people
A Research Study to Look at How Two Different Doses of CagriSema and One Dose of Semaglutide Help People Living With Obesity With or Without Type 2 Diabetes Lose Weight
Where
Brno-Stred, Dolní Břežany, Liberec, Náchod, Plzeň 3, Prague, Praha 22
Age
18 years and over
People
2,500 worldwide
Run by
Novo Nordisk A/S
See details and how to joinNCT07564414 · EU 2025-522488-14-00
Phase 3Taking people
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes
Where
Pardubice, Prague, Uherské Hradiště
Age
18 years and over
People
1,560 worldwide
Run by
Ascletis Pharma (China) Co., Limited
See details and how to joinNCT07743450
Phase 3Taking people
A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities
Where
Pardubice, Prague, Uherské Hradiště
Age
18 years and over
People
3,003 worldwide
Run by
Ascletis Pharma (China) Co., Limited
See details and how to joinNCT07743463