Follows a kidney nerve device in adults with uncontrolled high blood pressure
Observes real-world use of a kidney nerve treatment in adults with high blood pressure.
Plain-language title generated from the registry record
Registry title: Global Paradise System US Post Approval Study
Key facts
- Where
- Albany, Aurora, Austin, Boise, Boston, Bridgeport, Brooklyn, Buffalo, Chapel Hill, Charleston, Columbia, Coon Rapids, Dallas, Detroit, Durham, Erie, Fairfax, Gainesville, Harrisburg, Kansas City, Kingwood, Long Beach, Los Angeles, Loveland, Marietta, Marlton, Miami, Nashville, New Orleans, New York, Pensacola, Phildelphia, Raleigh, Sacramento, Salt Lake City, Santa Monica, Seattle, Spartanburg, Springfield, Stony Brook, Tampa, and Wichita, United StatesSee the 46 sites
Where in United States
- Albany Medical CenterAlbany, United StatesTaking people
- Rocky Mountain Regional VAMCAurora, United StatesTaking people
- Ascension SetonAustin, United StatesTaking people
- St. Luke's Regional Medical CenterBoise, United StatesTaking people
- Massachusetts General HospitalBoston, United StatesTaking people
- The Brigham and Women's HospitalBoston, United StatesTaking people
- Bridgeport HosptialBridgeport, United StatesTaking people
- NewYork-Presbyterian Brooklyn Methodist HospitalBrooklyn, United StatesTaking people
- University at BuffaloBuffalo, United StatesTaking people
- University of North Carolina at Chapel Hill School of MedicineChapel Hill, United StatesTaking people
- Medical University of South CarolinaCharleston, United StatesTaking people
- Prisma Health Richland HospitalColumbia, United StatesTaking people
- Metropolitan Heart Vascular InstituteCoon Rapids, United StatesTaking people
- Dallas VAMCDallas, United StatesTaking people
- Henry Ford HealthDetroit, United StatesTaking people
- Henry Ford St. John HospitalDetroit, United StatesTaking people
- Durham VA Health SystemDurham, United StatesTaking people
- AHN Saint VincentErie, United StatesTaking people
- Inova Fairfax HospitalFairfax, United StatesTaking people
- The Cardiac & Vascular InstituteGainesville, United StatesTaking people
- UPMC HarrisburgHarrisburg, United StatesTaking people
- Saint Luke's Mid America Heart InstituteKansas City, United StatesTaking people
- TCR InstituteKingwood, United StatesTaking people
- Tibor Rubin VA Medical CenterLong Beach, United StatesTaking people
- Cedars-Sinai Medical CenterLos Angeles, United StatesTaking people
- Medical Center of the RockiesLoveland, United StatesTaking people
- Wellstar Kennestone HospitalMarietta, United StatesTaking people
- Virtua HealthMarlton, United StatesTaking people
- University of Miami Health SystemMiami, United StatesTaking people
- Ascension Saint ThomasNashville, United StatesTaking people
- Touro InfirmaryNew Orleans, United StatesTaking people
- Columbia University Medical Center/New York-Presbyterian HospitalNew York, United StatesTaking people
- NYU Langone Health - Bellevue HosptialNew York, United StatesTaking people
- Ascension Sacred HeartPensacola, United StatesTaking people
- Penn MedicinePhildelphia, United StatesTaking people
- WakeMed Health and HospitalsRaleigh, United StatesTaking people
- Sutter Institute for Medical ResearchSacramento, United StatesTaking people
- UC Davis Medical CenterSacramento, United StatesTaking people
- St. Mark's HospitalSalt Lake City, United StatesTaking people
- Pacific Heart InstituteSanta Monica, United StatesTaking people
- Swedish Medical CenterSeattle, United StatesTaking people
- Spartanburg Regional Medical CenterSpartanburg, United StatesTaking people
- Southern Illinois University, Memorial Medical CenterSpringfield, United StatesTaking people
- Stony Brook MedicineStony Brook, United StatesTaking people
- Tampa Cardiovascular Interventions and ResearchTampa, United StatesTaking people
- Ascension Via Christi St. FrancisWichita, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- ReCor Medical, Inc.
- Trial code
- NCT06297291
- Record updated
- 16 October 2026
- Original description
The objective of the Global Paradise® System US Post Approval Study (US GPS) is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication. This system is comprised of a catheter, cable, balloon, and generator and has received FDA approval in the United States. Information collected in this study will be analyzed to better understand the long-term safety and effectiveness of treatment with the Paradise System for patients with high blood pressure.Read full original descriptionShow less
The Global Paradise® System US Post Approval Study (US GPS)
The objective of the Global Paradise® System US Post Approval Study (US GPS) is to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication. This system is comprised of a catheter, cable, balloon, and generator and has received FDA approval in the United States. Information collected in this study will be analyzed to better understand the long-term safety and effectiveness of treatment with the Paradise System for patients with high blood pressure.
Inclusion: Signed and dated study informed consent; Documented history of hypertension; Documented history of prior or current antihypertensive medication(s); Baseline seated office systolic BP at screening ≥ 140 mmHg; Mean pre-procedure home systolic BP of ≥ 135 mmHg; Estimated glomerular filtration rate (eGFR) of ≥30 mL/min/m2; RADIANCE CAP patients must provide signed and dated informed consent for inclusion in long-term follow-up. No other criteria are required for inclusion.
Exclusion: Subject is pregnant prior to index procedure\^ \^ If a treated subject becomes pregnant after ultrasound RDN procedure, the subject will be followed for outcomes; The ultrasound RDN procedure will be performed according to the IFU for the Paradise System and per the site's standard of care for interventional Procedures; Subject under the age of 18 years old at the time of consent; Patients who meet the following will be excluded from participation:.