Records how motor neuron disease looks different from person to person
Studies how motor neuron disease appears in adults at one Italian neurology clinic.
Plain-language title generated from the registry record
Registry title: Creation of a Clinical Database for the Study of Phenotypic Variability in Motor Neuron Diseases
Key facts
- Where
- Milan, ItalySee the site
Where in Italy
- Ospedale San LucaMilan, ItalyTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Istituto Auxologico Italiano
- Trial code
- NCT06318585
- Record updated
- 7 May 2025
- Original description
Study Description: Characterization of Motor Neuron Disease PhenotypesRead full original descriptionShow less
Creazione di un Database Clinico Per lo Studio Della variabilità Fenotipica Nella Malattia Del Motoneurone
Study Description: Characterization of Motor Neuron Disease Phenotypes
The goal of this observational study is to understand the clinical presentation of motor neuron disease (MND) in patients attending the Neurology Department of the Istituto Auxologico Italiano. The main questions it aims to answer are:
* What are the specific clinical phenotypes associated with MND? * How can these phenotypes contribute to a better understanding of the disease's underlying mechanisms and improve prognostic accuracy?
Participants will undergo:
* Clinical evaluation using validated scales * Neurophysiological and neuroradiological instrumental assessment * Neuropsychological evaluation * Collection of biological materials for genetic screening and biomarker assessment, if necessary.
Inclusion: diagnosis of ALS or other motor neuron disease.
Exclusion: refusal to participate to the study.