Sign in
Enrolling by invitationNo phase

Sleep health and heart and metabolism health in rural Appalachia and the Mississippi Delta

Looks at sleep problems and their links to heart and metabolic health in rural adults.

Key facts

Who runs it
Brigham and Women's Hospital
Where
Boston, United StatesSee the site
Trial code
Registry title
Adult Sleep Health in the Rural Appalachia and Mississippi Delta Region and Its Relationships With Cardiometabolic Health Disparities.
Status
Enrolling by invitation
People taking part
3,680 people, planned
Started
8 May 2024
Expected to end
31 Jan 2027
Type of study
Observational
Record updated
27 October 2025

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults who already take part in the RURAL Study in rural Appalachia and the Mississippi Delta. It measures their sleep health.

Age
25 Years to 65 Years
Sex
All sexes can join.

Main reasons for not taking part

  • People who are not in the Risk Underlying Rural Areas Longitudinal (RURAL) Study cannot join.

The registry criteria, word for word

Show all 2 criteriaShow less

Who can take part

  • All participants in the Risk Underlying Rural Areas Longitudinal (RURAL) Study will be eligible for enrollment in this ancillary study

Who cannot take part

  • None

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 25 and 65 years old?

Where in United States

  • Brigham and Women's HospitalBoston, United StatesEnrolling by invitation

About the trial

What the trial wants to find out

Rural communities in the southern U.S. suffer a disproportionate burden of morbidity and mortality from cardiometabolic disease, with traditional risk factors explaining only a modest proportion of the excess burden of disease. There is considerable evidence that multiple dimensions of sleep health, including sleep duration, efficiency, timing, and regularity, as well as the disorders sleep apnea and insomnia, affect cardiometabolic disease risk. However, there is currently a lack of systematically developed sleep data in rural populations. The RURAL Sleep Study is an ancillary study to a recently initiated longitudinal epidemiology study in rural Appalachia and Mississippi Delta (the RURAL Study). The RURAL Sleep Study will add measures of sleep health to the complex individual, social and environmental factors and health outcome measures being evaluated by the RURAL Study, by incorporating minimally burdensome measures of multiple dimensions of sleep health. The results are expected to inform health care providers, public health officials, and the general public of the prevalence, risk factors, and consequences of impaired sleep health in these rural communities, providing a critical basis for prevention, recognition, and management of sleep disorders and improvement of sleep and cardiometabolic health.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Sleep Health in the Rural South and Its Relationships With Cardiometabolic Health Disparities
Plain-language title
Sleep health and heart and metabolism health in rural Appalachia and the Mississippi DeltaGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 14 November 2026.
Fit questions
Built from NCT06336525, who can take part
Record updated
27 October 2025