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Predicting Treatment Side Effects in Older Adults With Head and Neck Cancer

Tests a tool predicting side effects in older adults with head and neck cancer.

Plain-language title generated from the registry record
Registry title: Predicting Toxicity in Elderly Patients With Head and Neck Cancer

Key facts

Where
Milan, ItalySee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 70 and 99 years old?

Source: NCT06344208, who can take part

Where in Italy

  • European Institute of OncologyMilan, ItalyTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
European Institute of Oncology
Trial code
NCT06344208
Record updated
24 March 2026
Original description
Predicting toxicity in elderly patients with head and neck cancer:Read full original descriptionShow less

Predicting Toxicity in Elderly Patients With Head and Neck Cancer: Validating a Disease-oriented Toxicity Predictive Tool and Integrating it With Available Screening Tools for Better Outcomes

Predicting toxicity in elderly patients with head and neck cancer:

validating a disease-oriented toxicity predictive tool and integrating it with avail-able screening tools for better outcomes.

Inclusion: Patients aged ≥ 70 years; Histological diagnosis of squamous cell or undifferentiated HNC in stage III-IV AJCC ed VIII (si-nonasal, nasopharynx, oral cavity, oropharynx, unknown primary with HPV pos, larynx and hy-popharynx) and candidated to curative non surgical treatment (radiotherapy alone, Chemora-diation with platinum salts; radiation+cetuximab); Evaluable disease accordingly to RECIST criteria 1.1; Willing of sign a written informed consent; Adequate organ function.

Exclusion: Patients who received systemic treatments in the past for other primary tumors; Patient with cancer in other sites than HN < than 2 years except for prostate cancer cT1-2, Gleason 3+3, NIMBC, initial Non Melanoma Skin Cancer, in situ cervical cancer); PS ECOG 3-4.

ClinicalTrials.gov NCT06344208