Morning versus evening strength exercise and blood sugar control in older adults
Compares morning and evening strength exercise on insulin response and sleep in older adults.
Key facts
- Who runs it
- University of Utah
- Where
- Salt Lake City, United StatesSee the site
- Trial code
- Registry title
- The Acute T-Rex (Timing of Resistance Exercise) Study
- Status
- Recruiting
- People taking part
- 20 people, planned
- Started
- 15 Nov 2023
- Planned end
- 31 Dec 2025
- Type of study
- Interventional, 2 groups
- Treatments tested
- Resistance Exercise Timing
- Record updated
- 3 April 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for generally healthy men and women aged 50-74 with overweight or obesity who do not exercise enough. It tests morning versus evening resistance exercise.
- Age
- 50 to 74 years
- Sex
- Men and women
- Disease stage
- Generally healthy; BMI ≥25 kg/m² and <45 kg/m²
- Earlier treatment
- Not on weight loss medication or other medications likely to affect energy balance. No bariatric surgery or extensive bowel resection in the past 2 years.
- Biomarker or test result
- HbA1c must not be above 6.5% (48 mmol/mol)
Main reasons for not taking part
- Uncontrolled heart, metabolic, kidney or lung disease
- Cancer treatment in the past 5 years
- Insomnia, sleep apnea or other sleep and circadian disorders
- Eating disorder now or in the past 2 years
- Weight change of 5% or more in the past 6 months
The registry criteria, word for word
Show all 14 criteriaShow less
Who can take part
- Men and women, all ethnicities, aged 50-74 years
- BMI ≥25 kg/m² and <45 kg/m²
- Weight stable (less than 5% change in the past 6 months)
- Generally healthy individuals
- Not meeting recommended activity guidelines for aerobic or resistance exercise
Who cannot take part
- Current use of weight loss medication or other medications likely to impact energy balance
- Bariatric surgery or extensive bowel resection in the past 2 years
- Uncontrolled cardiovascular, metabolic, renal, or pulmonary disease
- Cancer treatment in the past 5 years
- Untreated thyroid disease or other medical conditions affecting weight or energy metabolism
- Current or recent history (past 2 years) of eating disorder
- Diagnosis of insomnia, sleep apnea, or other sleep and circadian disorders
- HbA1c >6.5%
- Non-English speaking
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 74 years old?
Where in United States
- University of Utah HPER E BuildlingSalt Lake City, United StatesContact: Jason V Thomas, MSTaking people
About the trial
What the trial wants to find out
The primary aim of this study is to evaluate if a single bout of AM vs PM resistance exercise has different effects on insulin sensitivity and sleep. A randomized cross-over trial be used to compare resistance exercise at two different times of the day. Each condition will take place in a laboratory setting. Each condition will consist of exercise, overnight sleep, and oral glucose tolerance tests the following day. The AM exercise will occur ~1.5 hours after habitual wake, and PM exercise will occur ~11 hours after habitual wake. After a 2-6 week washout, participants will complete the other condition. The hypothesis is that PM exercise will be more beneficial than AM exercise in improving insulin sensitivity. This study could identify if there is a better time of day to perform resistance exercise to decrease risk of developing Type 2 Diabetes Mellitus.
The 2 groups in the trial
- AM Resistance ExerciseTreatment being tested
Resistance Exercise intervention taking place in the AM
Treatment: Resistance Exercise Timing
- PM Resistance ExerciseTreatment being tested
Resistance Exercise intervention taking place in the PM
Treatment: Resistance Exercise Timing
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Timing (AM v PM) of Acute Resistance Exercise on Glycemic Control in Older Adults: The Acute T-Rex Study
- Plain-language title
- Morning versus evening strength exercise and blood sugar control in older adultsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06366399, who can take part
- Record updated
- 3 April 2025