Type 2 diabetes trials in United States

In United States 393 Also abroad 1196

393 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Gut Microbiota in Metabolic Surgery
Where
Nashville
Age
21 years to 65 years
People
300
Run by
Vanderbilt University Medical Center
See details and how to joinNCT05000996
No phaseTaking people
Adapting and Assessing the Feasibility of a Telehealth Diabetes Prevention Program for Hispanic Adolescents
Where
Houston
Age
14 years to 16 years
People
40
Run by
Baylor College of Medicine
See details and how to joinNCT06943001
No phaseTaking people
PATHS-UP Health Behavior Self-monitoring Mobile App for Adolescents
Where
Houston
Age
12 years to 18 years
People
30
Run by
Baylor College of Medicine
See details and how to joinNCT06959901
No phaseTaking people
Continuous Glucose Monitoring for Self-Management of Type 2 Diabetes in Young Adults
Where
San Diego
Age
18 years to 45 years
People
45
Run by
San Diego State University
See details and how to joinNCT07065721
Phase 4Taking people
Permissive Versus Strict Intrapartum Glucose Management in Type 1 and Type 2 Diabetes (PRISM)
Where
Columbus
Age
18 years and over
People
44
Run by
Ohio State University
See details and how to joinNCT07293715
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes
Where
Anniston, Baltimore, Bellaire, Birmingham, Boston, Brownsville, Buffalo, Clarksville, Corpus Christi, Dallas, Dayton, Gulfport, Gurnee, Honolulu, Houston, Irvine, Louisville, McAllen, Milwaukee, Minneapolis, Myrtle Beach, Nashville, Needham, New Haven, New Orleans, Portland, Salt Lake City, San Antonio, San Diego, Schaumburg, Shavano Park, Sioux Falls, Skokie, Southlake, Springfield, Tucson, Tulsa, Union City, Walnut Creek, West Chester
Age
18 years and over
People
2,000 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351045 · EU 2025-523104-71-00
Phase 3Taking people
A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes
Where
Blackfoot, Brownsville, Clearwater, Columbia, Columbus, Dallas, Decatur, Edinburg, Guntersville, Houston, Irvine, Kansas City, Lake Charles, Lake Forest, Long Beach, Manassas, Metairie, Montclair, Morehead City, New Orleans, Norco, Norman, North Charleston, Oklahoma City, Olive Branch, Pasadena, Pembroke Pines, Pittsburgh, Port Orange, Rancho Cucamonga, Redmond, San Antonio, Sioux Falls, Springfield, Spring Valley, St. Petersburg, Suffolk, Tomball, Tucson, Tulsa, Union City, Washington D.C., Winston-Salem
Age
18 years and over
People
1,600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07351058 · EU 2025-523106-32-00
Phase 3Taking people
A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus
Where
Beltsville, Champaign, Chicago, Columbus, Escondido, Fargo, Franklin, Houston, Jacksonville, Kansas City, Las Vegas, Lincoln, Manassas, Oxon Hill, Portland, Renton, Smithfield, Somerset, Statesville, Stockbridge, Walnut Creek, Woodstock
Age
18 years and over
People
500 worldwide
Run by
AstraZeneca
See details and how to joinNCT07776509 · EU 2025-523295-23-00
Phase 3Taking people
Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight
Where
Bowie, Chickasha, Columbus, Dallas, Denison, DeSoto, Greenville, Houston, Johns Creek, McKinney, Meridian, Miami, Morehead City, North Richland Hills, Oak Brook, Orlando, Rochester, San Diego, The Villages, Woodstock
Age
18 years to 99 years
People
230 worldwide
Run by
Amgen
See details and how to joinNCT07871409
Phase 1/2Not yet taking people in United States
Relacorilant in Patients With Poorly Controlled Type 2 Diabetes and Autonomous Cortisol Secretion
Where
San Antonio
Age
18 years to 75 years
People
34
Run by
The University of Texas Health Science Center at San Antonio
See details and how to joinNCT07925801
No phaseTaking people
An Observational Study Called FINEROD to Learn More About the Use of the Treatment Finerenone Including How Safe it is and How Well it Works Under Real-world Conditions
Where
Many Locations
Age
18 years and over
People
50,000 worldwide
Run by
Bayer
See details and how to joinNCT06278207
No phaseTaking people
Linking Education, Produce Provision, and Community Referrals to Improve Diabetes Care (LINK)
Where
Columbus
Age
18 years and over
People
568
Run by
Ohio State University
See details and how to joinNCT05472441
No phaseTaking people
Using Ultromics EchoGo HFpEF Algorithm to Identify and Treat High Heart Failure Risk in Patients With Type 2 Diabetes
Where
Dallas
People
800
Run by
University of Texas Southwestern Medical Center
See details and how to joinNCT06593314
Early phase 1Enrolling by invitation
Truway Diagnostic Tools in Primary Care
Where
New York
People
200
Run by
Truway Health, Inc.
See details and how to joinNCT07209527
Phase 3Taking people
A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Where
Albuquerque, Baltimore, Canoga Park, Chicago, Cincinnati, Crystal River, Escondido, Evanston, Evansville, Flint, Greensboro, Houston, Lecanto, Louisville, Miramar, Modesto, New Port Richey, New York, Norfolk, Omaha, Pembroke Pines, Rochester, Sacramento, San Antonio, Skokie, Tustin, Walnut Creek, West Hills, Wilmington
Age
18 years and over
People
954 worldwide
Run by
Pfizer
See details and how to joinNCT07595549 · EU 2026-525318-75-00
Phase 3Taking people
A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes
Where
Ammon, Atlanta, Beaumont, Corpus Christi, Decatur, Edinburg, Nashville, Sacramento, San Diego, Shavano Park, Smithfield, Stamford, Syracuse, The Bronx, Topeka, Tulsa, Victoria
Age
10 years to 17 years
People
170 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07668336 · EU 2025-524811-35-00
Phase 3Taking people
A Phase III Study to Evaluate the Efficacy and Safety of Petrelintide in Participants With Overweight or Obesity and Type 2 Diabetes
Where
Los Angeles, Manassas
Age
18 years and over
People
600 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT07843485 · EU 2026-526189-25-00
Phase 3Taking people
Maridebart Cafraglutide Versus Semaglutide in Participants With Type 2 Diabetes
Where
Arlington, Miami, Miami Lakes, Pompano Beach, Redmond, San Diego, Winter Park
Age
18 years and over
People
1,300 worldwide
Run by
Amgen
See details and how to joinNCT07866066 · EU 2025-523772-22-00
No phaseNot yet taking people in United States
Community Health Worker Nutrition Self-Management Support for Cardio-Kidney-Metabolic Health
Where
Boynton Beach
Age
18 years and over
People
200
Run by
Florida International University
See details and how to joinNCT07918508
No phaseNot yet taking people in United States
Inter-Arm Differences in Continuous Glucose Monitor Readings in Adults With Diabetes
Where
Stockton
Age
18 years and over
People
60
Run by
University of the Pacific
See details and how to joinNCT07920341
Phase 2Taking people
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Where
Brownsburg, Dayton, Houston, Lawrenceville, Long Island City, Mesquite, Morehead City, Norman, Ocala, Oviedo, Pennington, Phoenix, Redmond, Rexburg, Round Rock, Santa Ana, Scottdale, Shavano Park, Shelby, Staten Island, Union City, Weslaco, West Seneca, Woodstock
Age
18 years to 75 years
People
200 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT06897475 · EU 2024-520328-27-00
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes
Where
Albuquerque, Aurora, Austin, Birmingham, Bridgeport, Canoga Park, Chesterfield, Columbia, Corpus Christi, Cullman, Dallas, Daytona Beach, Delray Beach, Dunwoody, Eatontown, Escondido, Fargo, Fleming Island, Fort Worth, Greenbrae, Greensboro, Hamden, Honolulu, Houston, Indianapolis, Inverness, Jacksonville, Lawrenceville, Lima, Long Beach, Long Island City, Los Alamitos, Los Angeles, Macon, Mesquite, Metairie, Miami, Monroe, Morehead City, Mt. Dora, Mt. Pleasant, New Bedford, Ogden, Pembroke Pines, Pittsburgh, Plano, Portland, San Antonio, Sandy City, Santa Clarita, Skokie, Springfield, Spring Valley, Tucson, Uniontown, Walnut Creek, Warren Township, Wilmington, Winter Park
Age
18 years and over
People
1,035 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07282600 · EU 2025-523658-15-00
Phase 3Taking people
A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin
Where
Atlantis, Birmingham, Boston, Bridgeport, Chapel Hill, Chesterfield, Chicago, Cincinnati, Columbia, Dallas, Doral, Dunwoody, Fleming Island, Gainesville, Greensboro, Houston, Idaho Falls, Irvine, Jacksonville, Kingwood, La Jolla, La Mesa, Lexington, Lima, Miami, Mission, Missouri City, Monroe, Morehead City, Myrtle Beach, New Haven, New York, Phoenix, Pittsburgh, Rolling Hills Estates, Sacramento, Saint Augustine, San Antonio, San Diego, Santa Ana, Scottsdale, Shavano Park, Southfield, Topeka, Troy, Tucson, Tustin, Waltham, Waterbury, Weslaco, West Des Moines, West Palm Beach, Wilmington, Wylie
Age
18 years and over
People
900 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07392190 · EU 2025-523659-73-00
No phaseTaking people
Clinical Decision Support for SGLT2i After AKI in Type 2 Diabetes
Where
Minneapolis
Age
30 years to 75 years
People
250
Run by
University of Minnesota
See details and how to joinNCT07868666
Phase 3Taking people
A Study of EloraTZP in Adult Participants With Obesity or Overweight and Type 2 Diabetes
Where
Arlington, Aurora, Austin, Dalton, Eunice, Fort Worth, Honolulu, Houston, Indianapolis, Los Alamitos, Los Angeles, Marrero, Midland, Mission, New York, Pembroke Pines, Redmond, San Antonio, St Louis, Tucson, Tyler, Warren Township, Weston
Age
18 years and over
People
1,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07881458 · EU 2026-527230-31-00