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Smartphone app to help people with sleep apnea keep using CPAP

Tests a phone app to support nightly CPAP use in adults with obstructive sleep apnea.

Key facts

Who runs it
Mayo Clinic
Where
Rochester and Scottsdale, United StatesSee the 2 sites
Trial code
Registry title
App-Based Optimization of Long-Term CPAP Adherence and Quality of Life
Status
Recruiting
People taking part
40 people, planned
Started
1 Jun 2025
Planned end
Oct 2026
Type of study
Interventional
Treatments tested
  • SleepWell24 Application
Record updated
14 August 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults newly diagnosed with obstructive sleep apnea (OSA) who are prescribed CPAP. They will use the SleepWell24 smartphone app and a wrist sensor to help them use CPAP more.

Age
18 years and older
Sex
All sexes. The trial aims for a balance of men and women.
Disease stage
Newly diagnosed OSA, confirmed by a sleep study in a lab or at home. Mild (apnea hypopnea index 5-14) and more severe (≥ 15) OSA are both included.
Earlier treatment
Must be prescribed continuous or auto-titrated CPAP. People who have used CPAP before cannot join.
Biomarker or test result
Apnea hypopnea index (number of breathing pauses per hour of sleep) of 5-14 or ≥ 15.

Main reasons for not taking part

  • Previous CPAP use, or not using the ResMed Airsense 10 device
  • High-dose benzodiazepines (more than 1 mg lorazepam a night) or daily opioid use at night
  • Past treatment or referral for claustrophobia (fear of closed spaces)
  • Night shift or rotating day and night shift work
  • Pregnant, trying to get pregnant, or breastfeeding

The registry criteria, word for word

Show all 15 criteriaShow less

Who can take part

  • In both trials of Aim 2, twenty adults (≥18 years) per trial will be recruited who are newly diagnosed with OSA and speak English
  • In both trials, we will purposely recruit samples balanced by biological sex and OSA severity (apnea hypopnea index: 5-14 vs. ≥ 15)
  • Inclusion Criteria are the same for both Aim 2 trials; Adult patients from MCCSM sites who:; Are diagnosed with OSA based on clinical diagnostic testing via laboratory or home-based sleep study; Own and have the functional and cognitive ability to use an Apple (iOS9 or higher) or Android (4.2 or higher) smartphone with minimal to no assistance; Are prescribed continuous or auto-titrated CPAP; Agree to using a smartphone application and wearable wrist sensor; and; Speak and read English

Who cannot take part

  • Daily opioid medication use at night;'
  • Previous documented history of treatment/referral for claustrophobia
  • Previous CPAP use
  • Have any conditions that would impede full participation (e.g., communication or cognitive impairments that limit ability to read and/or follow directions, other acute or severe health, cognitive, or psychological conditions)
  • Unwilling to complete study measures and engage with SleepWell24
  • Refuse to not use the Fitbit application during the study trial
  • Currently participating in other lifestyle programs (e.g. active, formal weight loss program or research study; smoking cessation program, etc.)
  • Decide to use a different PAP device than ResMed Airsense 10
  • Prescribed high-dose benzodiazepines (equivalent to > 1 mg lorazapam/night)
  • Unwilling to discontinue use of any current wearable sensor for the duration of the trial
  • Currently engaging in shiftwork defined as night shift or rotating day and night shifts; and
  • Currently pregnant, trying to conceive, or breastfeeding

Where in United States

  • Mayo Clinic in RochesterRochester, United StatesContact: Rebecca K RaTaking people
  • Mayo Clinic in ArizonaScottsdale, United StatesContact: Betty MonariTaking people

About the trial

What the trial wants to find out

The purpose of this study is to optimize the time of CPAP usage to at least 6 hours a night for 6 nights per week for people who have OSA with the help of a smartphone application called SmartWell24. This application aims to target CPAP adherence.

The group in the trial

  • SleepWell24 Smart ApplicationTreatment being tested

    This group will consists of participates who will be on study for 8 weeks using the Sleepwell24 application. Once 20 people are enrolled on the 8 week cohort, a 6 month cohort will open up for 20 different participants.

    Treatment: SleepWell24 Application

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
An App-Based, Precision Medicine Approach to Optimize Long-Term CPAP Adherence and Quality of Life
Plain-language title
Smartphone app to help people with sleep apnea keep using CPAPGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 14 November 2026.
Record updated
14 August 2026