Offers HIV testing and prevention referrals to emergency department patients in South Africa
Tests whether HIV testing in emergency departments reaches people with HIV or high risk.
Plain-language title generated from the registry record
Registry title: Universal Test and Connect for HIV Service Delivery in South Africa
Key facts
- Where
- Cape Town, South AfricaSee the site
Where in South Africa
- Gugulethu Community Health CentreCape Town, South AfricaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Johns Hopkins University
- Trial code
- NCT06408142
- Record updated
- 30 January 2026
- Original description
The goal of this study is to determine how many patients with HIV or at high risk of getting HIV attend the Emergency Department (ED) in South Africa (SA). The investigators will integrate HIV assessment in the ED and see how many people who would be a candidate for a drug that prevents HIV (PrEP). Universal test and connect (UTC) is a strategy that universally tests all patients and connects patients to long-term care, whether HIV positive or negative, including referrals for PrEP. The investigator's goal is to use UTC across two busy 24-hr EDs in Cape Town, SA.Read full original descriptionShow less
Universal Test and Connect for HIV Service Delivery in South Africa and Baltimore
The goal of this study is to determine how many patients with HIV or at high risk of getting HIV attend the Emergency Department (ED) in South Africa (SA). The investigators will integrate HIV assessment in the ED and see how many people who would be a candidate for a drug that prevents HIV (PrEP). Universal test and connect (UTC) is a strategy that universally tests all patients and connects patients to long-term care, whether HIV positive or negative, including referrals for PrEP. The investigator's goal is to use UTC across two busy 24-hr EDs in Cape Town, SA.
Inclusion: Patients attending the Emergency Department; Ages > or = 12 years old in South Africa; For subset that participate in PrEP choice trial, inclusion criteria will be to ensure that they meet PrEP eligibility criteria and do not have any contraindications to PrEP (kidney disease, acute HIV signs or symptoms, already taking PrEP); Nurses, physicians, or advanced practice providers (APPs) who work regularly in the Emergency Department at one of the clinical sites; Consent to a recorded in-depth interview and/or Normalizing Process Theory (NPT) survey.
Exclusion: Patients unable to provide written informed consent - i.e., have a depressed level of consciousness (head trauma or concurrent alcohol/substance abuse), determined as critically ill (triage score of "emergent"), or; do not speak a language spoken by the study team (English, Afrikaans, and Xhosa); In-depth interviews and surveys to providers:; Providers who have already been interviewed (if working at both clinical sites); Providers who do not consent to an interview or a survey.