Brain feedback training to reduce food cravings in people with overweight or obesity
Tests brain feedback training for food cravings in adults with overweight or obesity.
Key facts
- Who runs it
- Yale University
- Where
- New Haven, United StatesSee the site
- Trial code
- Registry title
- Craving Network Neurofeedback
- Status
- Recruiting
- People taking part
- 50 people, planned
- Started
- 27 Nov 2024
- Expected to end
- 31 Mar 2027
- Type of study
- Interventional, 2 groupsOne group gets a sham (pretend) treatment, for comparison.
- Treatments tested
- Experimental feedback
- Control feedback
- Record updated
- 3 December 2025
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with overweight or obesity and strong food craving. It tests whether brain neurofeedback can change craving and eating.
- Age
- 18 to 60 years
- Sex
- All sexes can join.
- Disease stage
- Body mass index above 25 kg/m2 (overweight or obesity).
- Earlier treatment
- Cannot have used anti-obesity medications now or in the past 6 months. Cannot have lost more than 10% of body weight in the past 6 months.
- Biomarker or test result
- Food Craving Inventory score above 2.37.
Main reasons for not taking part
- Use of anti-obesity medications now or in the past 6 months
- Weight loss of more than 10% in the past 6 months
- Nicotine use
- Current neurological or psychiatric diagnosis
- Obesity-related diseases such as type-2 diabetes
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Ages 18 to 60 years
- Body mass index >25 kg/m2
- >2.37 Food Craving Inventory score
Who cannot take part
- Current or past 6 months use of anti-obesity medications
- Current diagnosis of neurological or psychiatric disorder
- Obesity-related diseases such as type-2 diabetes
- Weight-reduced state defined as >10% weight reduction in the past 6 months
- Nicotine use
- Contraindications to MRI
- Baseline scanning with motion >0.15mm frame to frame displacement
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Where in United States
- Yale MRRC Anlyan CenterNew Haven, United StatesContact: Kathleen A Garrison, PhDTaking people
About the trial
What the trial wants to find out
This project tests whether individuals with overweight or obesity and high craving can learn to change their brain response to food cues using neurofeedback, to impact their craving and eating behavior.
The 2 groups in the trial
- NeurofeedbackTreatment being tested
Three imaging (fMRI) sessions of experimental feedback.
Treatment: Experimental feedback
- Control neurofeedbackSham treatment, for comparison
Three imaging (fMRI) sessions of sham feedback.
Treatment: Control feedback
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Connectome-based Neurofeedback of the Craving Network to Reduce Food Cue Reactivity
- Plain-language title
- Brain feedback training to reduce food cravings in people with overweight or obesityGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT06426693, who can take part
- Record updated
- 3 December 2025